FAQ

timiperone

Known as: 4'-fluoro-4-(4-(2-thioxo-1-benzimidazolinyl)piperidino)butyrophenone, 4-(4-(2,3-dihydro-2-thioxo-1H-benzimidazol-1-yl)-1-piperidinyl)-1-(4-fluorophenyl)-1- butanone 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2016
02419792016

Related topics

Related topics

3 relations

Broader (3)

AntiemeticsAntipsychotic AgentsButyrophenones

Related mentions per year

Related mentions per year

1950-2018
1960198020002020
timiperone
Antipsychotic Agents
Antiemetics
Butyrophenones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Atypical properties of several classes of antipsychotic drugs on the basis of differential induction of Fos-like immunoreactivity in the rat brain.
Acute administration of typical and atypical antipsychotics has been reported to induce regionally distinct patterns of c-Fos… (More)
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1998
1998
Carbonyl reduction of timiperone in human liver cytosol.
This in vitro study using human liver enzymes was undertaken in order to compare the mechanism of metabolic reduction of… (More)
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1998
1998
Plasma concentrations of timiperone and its reduced metabolite in the patients on timiperone.
Plasma levels of timiperone (TIM) and reduced timiperone (RTIM) were determined in 10 schizophrenic patients who were treated… (More)
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1989
1989
Prophylactic effects of neuroleptics in symptom-free schizophrenics: a comparative dose-response study of timiperone and sulpiride.
Remitted schizophrenic outpatients were prophylactically treated to prevent relapse with three different doses of timiperone or… (More)
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1988
1988
[Antiemetic effect of timiperone and methylprednisolone in cisplatin-induced emesis].
As we already reported, timiperone, a new neuroleptic agent of the butyrophenone group, has a strong antiemetic effect against… (More)
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1986
1986
[Antiemetic therapy with timiperone in cisplatin-induced vomiting].
A new neuroleptic drug, Timiperone, is able to exert an antiapomorphine effect at doses smaller than cataleptogenic doses… (More)
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1983
1983
Comparison of efficacy of timiperone, a new butyrophenone derivative, and clocapramine in schizophrenia: a multiclinic double-blind study.
The clinical efficacy and safety of timiperone, a new butyrophenone derivative, on chronic schizophrenia was compared with… (More)
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1982
1982
Comparison of efficacy of a new butyrophenone derivative, timiperone and perphenazine in schizophrenia by a multicentre controlled study.
The efficacy of timiperone in schizophrenia as compared with perphenazine was assessed in a double-blind fashion in 205 patients… (More)
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1981
1981
Disposition and metabolism of timiperone in the rat, dog, and monkey.
The disposition and metabolism of timiperone (TP), a new butyrophenone antipsychotic, were studied in the rat, dog, and monkey… (More)
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1979
1979
Effect of timiperone on 3H-spiroperidol binding to rat striatal dopamine receptors.
The effects of timiperone, its metabolites and related compounds on specific 3H-spiroperidol binding to dopamine receptors in the… (More)
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