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timiperone

Known as: 4'-fluoro-4-(4-(2-thioxo-1-benzimidazolinyl)piperidino)butyrophenone, 4-(4-(2,3-dihydro-2-thioxo-1H-benzimidazol-1-yl)-1-piperidinyl)-1-(4-fluorophenyl)-1- butanone 
 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

AntiemeticsAntipsychotic AgentsButyrophenones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Exploring surface photoreaction dynamics using pixel imaging mass spectrometry (PImMS).
A new technique for studying surface photochemistry has been developed using an ion imaging time-of-flight mass spectrometer in… Expand
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2008
2008
4-Hydroxy-1-(3-pyridyl)-1-butanone-releasing DNA adducts in lung, lower esophagus and cardia of sudden death victims.
4-Hydroxy-l-(3-pyridyl)-l-butanone (HPB)-releasing adducts are formed by metabolic activation of N'-nitrosonornicotine and 4… Expand
Highly Cited
1998
Highly Cited
1998
MUC1 is a novel marker for the type II pneumocyte lineage during lung carcinogenesis.
Abnormalities in mucin-type glycoprotein expression have been documented in a variety of cancers, identifying these molecules as… Expand
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1998
1998
Carbonyl reduction of timiperone in human liver cytosol.
This in vitro study using human liver enzymes was undertaken in order to compare the mechanism of metabolic reduction of… Expand
1998
1998
Plasma concentrations of timiperone and its reduced metabolite in the patients on timiperone
Plasma levels of timiperone (TIM) and reduced timiperone (RTIM) were determined in 10 schizophrenic patients who were treated… Expand
1998
1998
Hypogammaglobulinemia during antipsychotic therapy
Abstract Hypogammaglobulinemia in a 22‐year‐old woman with brief psychotic disorder developed during antipsychotic therapy… Expand
1997
1997
Effect of hyperprolactinemia induced by neuroleptic agent, timiperone, on porphyrin content of mouse harderian gland.
The histology and porphyrin content of the Harderian gland and the serum prolactin levels were examined in male B6C3F1 mice… Expand
1989
1989
Prophylactic effects of neuroleptics in symptom-free schizophrenics: A comparative dose-response study of timiperone and sulpiride
Remitted schizophrenic outpatients were prophylactically treated to prevent relapse with three different doses of timiperone or… Expand
1983
1983
Comparison of Efficacy of Timiperone, a New Butyrophenone Derivative, and Clocapramine in Schizophrenia: A Multiclinic Double-Blind Study
The clinical efficacy and safety of timiperone, a new butyrophenone derivative, on chronic schizophrenia was compared with… Expand
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1981
1981
Disposition and metabolism of timiperone in the rat, dog, and monkey.
The disposition and metabolism of timiperone (TP), a new butyrophenone antipsychotic, were studied in the rat, dog, and monkey… Expand
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