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tilisolol

Known as: 1(2H)-Isoquinolinone, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-2-methyl-, 4-(3(tert-butylamino)-2-hydroxypropoxy)-N-methylisocarbostyril 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Adrenergic beta-AntagonistsAnti-Arrhythmia AgentsIsoquinolines

Narrower (1)

N 696

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Transport of timolol and tilisolol in rabbit corneal epithelium.
The purpose of this study is to characterize the transport of tilisolol and timolol through the corneal epithelium, which is… 
2003
2003
One-side-coated insert as a unique ophthalmic drug delivery system.
2001
2001
Ocular absorption behavior of palmitoyl tilisolol, an amphiphilic prodrug of tilisolol, for ocular drug delivery.
The objective of this study was to examine the ocular absorption behavior of an amphiphilic prodrug after instillation onto the… 
2001
2001
Controlled release and ocular absorption of tilisolol utilizing ophthalmic insert-incorporated lipophilic prodrugs.
2000
2000
Pharmacokinetic prediction of the ocular absorption of an instilled drug with ophthalmic viscous vehicle.
We previously developed an in vivo pharmacokinetic model that accounts for the corneal diffusion in albino rabbits and predicts… 
1999
1999
Characterization of Ocular Pharmacokinetics of Beta-Blockers Using a Diffusion Model After Instillation
AbstractPurpose. To characterize the ocular pharmacokinetics of beta-blockers (timolol and tilisolol) after instillation in the… 
1999
1999
Characterization of ocular pharmacokinetics of tilisolol after instillation into anesthetized rabbits.
The purpose of this study was to characterize the ocular pharmacokinetics of a beta-blocker, tilisolol, after instillation into… 
1997
1997
Effects of tilisolol, a nonselective beta-adrenergic blocker, on the membrane currents of isolated guinea pig ventricular myocytes.
The effects of tilisolol, a nonselective beta-adrenoceptor blocker, on transmembrane ionic currents were studied in single guinea… 
1996
1996
Tilisolol hydrochloride dilates coronary arteries through an ATP-sensitive K+-channel opening mechanism in dogs
SummaryTilisolol is a beta-blocking agent with vasodilatory properties that was recently shown to possess a potassium (K… 
1995
1995
Ophthalmic Preservatives as Absorption Promoters for Ocular Drug Delivery
The effects of ophthalmic preservatives on the drug permeability through isolated ocular membranes of albino rabbits were… 
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