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thyrotropin alfa

Known as: Human TSH, Recombinant, Recombinant Human TSH, Thyrotrophin-alfa 
A highly purified recombinant glycoprotein form of human THYROID-STIMULATING HORMONE, produced by recombinant DNA technology comprising two non… 
National Institutes of Health

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Drug AllergyFollitropin AlfaGlycoprotein Hormones, alpha SubunitIn Blood

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Thyrogen

Papers overview

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Highly Cited
2009
Highly Cited
2009
Assessment of the incremental value of recombinant thyrotropin stimulation before 2-[18F]-Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography imaging to localize residual…
PURPOSE The purpose of the study was to assess prospectively the impact of recombinant human TSH (rhTSH) administration on… 
Highly Cited
2007
Highly Cited
2007
Monitoring thyroglobulin in a sensitive immunoassay has comparable sensitivity to recombinant human tsh-stimulated thyroglobulin in follow-up of thyroid cancer patients.
CONTEXT Most thyroglobulin (Tg) assays have a sensitivity of 0.5-1 ng/ml. A minority of patients with undetectable T4-suppressed… 
Review
2006
Review
2006
A comparison of short-term changes in health-related quality of life in thyroid carcinoma patients undergoing diagnostic evaluation with recombinant human thyrotropin compared with thyroid hormone…
CONTEXT Thyroid carcinoma requires lifelong monitoring with serum thyroglobulin, radioactive iodine whole body scanning, and… 
Highly Cited
2005
Highly Cited
2005
A single recombinant human thyrotropin-stimulated serum thyroglobulin measurement predicts differentiated thyroid carcinoma metastases three to five years later.
CONTEXT Testing for residual differentiated thyroid carcinoma relies heavily upon recombinant human (rh)TSH-stimulated serum… 
Review
2005
Review
2005
rhTSH-aided radioiodine ablation and treatment of differentiated thyroid carcinoma: a comprehensive review.
Traditionally, withdrawal of thyroid hormone has been used to attain the increase in serum TSH concentrations that are believed… 
Review
2003
Review
2003
A consensus report of the role of serum thyroglobulin as a monitoring method for low-risk patients with papillary thyroid carcinoma.
Recent studies have provided new information regarding the optimal surveillance protocols for low-risk patients with… 
Highly Cited
2003
Highly Cited
2003
Radioiodine treatment with 30 mCi after recombinant human thyrotropin stimulation in thyroid cancer: effectiveness for postsurgical remnants ablation and possible role of iodine content in L…
The main steps in the management of differentiated thyroid cancer are thyroidectomy, treatment with iodine-131 ((131)I), and… 
Highly Cited
2003
Highly Cited
2003
Comparison of radioiodine biokinetics following the administration of recombinant human thyroid stimulating hormone and after thyroid hormone withdrawal in thyroid carcinoma
Iodine kinetics were studied in patients with differentiated thyroid cancer while euthyroid under exogenous thyroid stimulating… 
Highly Cited
2001
Highly Cited
2001
Prediction of disease status by recombinant human TSH-stimulated serum Tg in the postsurgical follow-up of differentiated thyroid carcinoma.
Stimulation with recombinant human TSH (rhTSH) has been introduced in clinical practice as an effective alternative to thyroid… 
Highly Cited
1994
Highly Cited
1994
Diagnostic use of recombinant human thyrotropin in patients with thyroid carcinoma (phase I/II study).
Current diagnostic studies [radioiodine uptake and serum thyroglobulin (Tg) levels] for residual or metastatic thyroid tissue in… 
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