Skip to search formSkip to main contentSkip to account menu

thymalfasin

Known as: Thymosin alpha 1, alpha1-thymosin, Thymosin alpha1 
A synthetic analogue of thymosin-alpha-1, a 28-amino acid protein derived from the precursor protein prothymosin-alpha. Exhibiting a variety of… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

Antineoplastic AgentsImmunologic AdjuvantsThymosin
Hepatitis Banalogs & derivatives

Narrower (1)

Zadaxin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1989
Highly Cited
1989
The thymus in acquired immune deficiency syndrome. Comparison with other types of immunodeficiency diseases, and presence of components of human immunodeficiency virus type 1.
The authors studied thymus specimens taken at autopsy from eight acquired immune deficiency syndrome (AIDS) patients and compared… 
Highly Cited
1989
Highly Cited
1989
Isolation and partial sequencing of the human prothymosin alpha gene family. Evidence against export of the gene products.
Prothymosin alpha and thymosin alpha 1 are believed to be thymus-derived, hormone-like materials with immunomodulatory functions… 
Highly Cited
1989
Highly Cited
1989
Characterization of the immunoregulatory properties of thymosin alpha 1 on interleukin-2 production and interleukin-2 receptor expression in normal human lymphocytes.
Highly Cited
1985
Highly Cited
1985
Primary structure of rat thymus prothymosin alpha.
The primary structure of prothymosin alpha from rat thymus, containing 113 amino acid residues, is reported as follows: (formula… 
Highly Cited
1984
Highly Cited
1984
Prothymosin alpha: isolation and properties of the major immunoreactive form of thymosin alpha 1 in rat thymus.
A polypeptide containing approximately equal to 112 amino acid residues, with the thymosin alpha 1 sequence at its NH2 terminus… 
Highly Cited
1984
Highly Cited
1984
The human thymic microenvironment: cortical thymic epithelium is an antigenically distinct region of the thymic microenvironment.
The thymic microenvironment is a complex tissue essential for normal T cell maturation. Prothymocytes in the subcapsular cortical… 
Highly Cited
1983
Highly Cited
1983
Immunological characterization of homosexual males.
To help clarify the nature and pathogenesis of the syndrome of severely opportunistic infection associated with immune deficiency… 
Highly Cited
1983
Highly Cited
1983
Elevated serum thymosin alpha 1 levels associated with evidence of immune dysregulation in male homosexuals with a history of infectious diseases or Kaposi's sarcoma.
Highly Cited
1982
Highly Cited
1982
Age-related changes in localization of thymosin in the human thymus.
Using an indirect fluorescent antibody technique, localization of thymosin alpha 1, thymosin beta 3 and thymosin fraction 6 was… 
Highly Cited
1980
Highly Cited
1980
Production of biologically active N alpha-desacetylthymosin alpha 1 in Escherichia coli through expression of a chemically synthesized gene.
Thymosin alpha 1, an immune restorative polypeptide hormone, was synthesized in Escherichia coli by using recombinant DNA cloning… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)