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thymalfasin

Known as: Thymosin alpha 1, alpha1-thymosin, Thymosin alpha1 
A synthetic analogue of thymosin-alpha-1, a 28-amino acid protein derived from the precursor protein prothymosin-alpha. Exhibiting a variety of… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

Antineoplastic AgentsImmunologic AdjuvantsThymosin
Hepatitis Banalogs & derivatives

Narrower (1)

Zadaxin

Papers overview

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Highly Cited
2005
Highly Cited
2005
Proteomic patterns and prediction of glomerulosclerosis and its mechanisms.
Protein expression profiles linked to sclerosis in the 5/6 nephrectomy (Nx) rat model of focal segmental glomerulosclerosis were… 
Highly Cited
1997
Highly Cited
1997
Expression of Specific Tubulin Isotypes Increases during Regeneration of Injured CNS Neurons, But Not after the Application of Brain-Derived Neurotrophic Factor (BDNF)
Axonal regrowth after injury is accompanied by changes in the expression of tubulin, but the contributions of substrate molecules… 
Highly Cited
1993
Highly Cited
1993
Thymosin beta-4 expression is correlated with metastatic capacity of colorectal carcinomas.
We constructed a "non-metastatic cell (SW837)--metastatic cell (PMCO1)" subtraction library and identified one cDNA that was… 
Highly Cited
1989
Highly Cited
1989
The thymus in acquired immune deficiency syndrome. Comparison with other types of immunodeficiency diseases, and presence of components of human immunodeficiency virus type 1.
The authors studied thymus specimens taken at autopsy from eight acquired immune deficiency syndrome (AIDS) patients and compared… 
Highly Cited
1989
Highly Cited
1989
Isolation and partial sequencing of the human prothymosin alpha gene family. Evidence against export of the gene products.
Prothymosin alpha and thymosin alpha 1 are believed to be thymus-derived, hormone-like materials with immunomodulatory functions… 
Highly Cited
1985
Highly Cited
1985
Primary structure of rat thymus prothymosin alpha.
The primary structure of prothymosin alpha from rat thymus, containing 113 amino acid residues, is reported as follows: (formula… 
Highly Cited
1984
Highly Cited
1984
Prothymosin alpha: isolation and properties of the major immunoreactive form of thymosin alpha 1 in rat thymus.
A polypeptide containing approximately equal to 112 amino acid residues, with the thymosin alpha 1 sequence at its NH2 terminus… 
Highly Cited
1983
Highly Cited
1983
Immunological characterization of homosexual males.
To help clarify the nature and pathogenesis of the syndrome of severely opportunistic infection associated with immune deficiency… 
Highly Cited
1982
Highly Cited
1982
Age-related changes in localization of thymosin in the human thymus.
Using an indirect fluorescent antibody technique, localization of thymosin alpha 1, thymosin beta 3 and thymosin fraction 6 was… 
Highly Cited
1979
Highly Cited
1979
The chemistry and biology of thymosin. II. Amino acid sequence analysis of thymosin alpha1 and polypeptide beta1.
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