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thio-Cl-IB-MECA

Known as: thio-2-chloro-N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Adenosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats.
A3 adenosine receptor (A3AR) is recognized as a novel therapeutic target for ischemic injury; however, the mechanism underlying… Expand
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2008
2008
Adenosine induces a cholinergic tracheal reflex contraction in guinea pigs in vivo via an adenosine A1 receptor-dependent mechanism.
Adenosine induces dyspnea, cough, and airways obstruction in asthma, a phenomenon that also occurs in various sensitized animal… Expand
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Review
2005
Review
2005
First joint Italian–German purine club meeting “Progress in Purinergic Receptor Pharmacology and Function”
The first joint meeting of the Italian and German Purine Clubs took place in Chieti (Italy) between September 18–20 of this year… Expand
2004
2004
Negative chronotropic response to adenosine receptor stimulation in rat right atria after run training
1. The aim of the present study was to evaluate the potency and maximal responses (Emax) to the adenosine receptor agonists N6… Expand
Highly Cited
2002
Highly Cited
2002
Identification by Site-directed Mutagenesis of Residues Involved in Ligand Recognition and Activation of the Human A3 Adenosine Receptor*
Ligand recognition has been extensively explored in G protein-coupled A1, A2A, and A2B adenosine receptors but not in the… Expand
2002
2002
Adenosine A(3) receptor-mediated potentiation of mucociliary transport and epithelial ciliary motility.
To examine the effect of adenosine A(3) receptor stimulation on airway mucociliary clearance, we measured transport of Evans blue… Expand
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2002
2002
2-Chloro-N(6)-cyclopentyladenosine, adenosine A(1) receptor agonist, antagonizes the adenosine A(3) receptor.
The potent adenosine A(1) receptor agonists, N(6)-cyclopentyladenosine (CPA) and 2-chloro-N(6)-cyclopentyladenosine (CCPA), were… Expand
2001
2001
Involvement of A(3) receptors in the potentiation by adenosine of the inhibitory effect of theophylline on human eosinophil degranulation: possible novel mechanism of the anti-inflammatory action of…
The current use of theophylline in asthma is based on both the bronchodilatory and the anti-inflammatory effects. The exact… Expand
Highly Cited
1998
Highly Cited
1998
Selective activation of adenosine A3 receptors with N6-(3-chlorobenzyl)-5'-N-methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via KATP channel activation.
OBJECTIVE The aim of this study was to characterize the adenosine A3 receptor agonist, N6-(3-chlorobenzyl)-5'-N… Expand
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