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thiazesim

Known as: 5-(2-dimethylaminoethyl)-2,3-dihydro- 2-phenyl-1,5-benzothiazepin-4(5H)-one 
National Institutes of Health

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1 relation

Broader (1)

Thiazepines

Papers overview

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2012
2012
A Novel Ionic Liquid Mediated Synthesis of 2,3-Dihydro-1,5-benzothiazepines Using Recyclable Catalyst Amberlyst-15®.
1,5-Benzothiazepine derivatives have been reported to be well known therapeutic agents due to their wide range of pharmacological… 
1979
1979
The effects of two "anti-aggressive" compounds, an indenopyridine and a benzothiazepin, on shock-induced defensive fighting in rats.
1972
1972
Conditioned avoidance deficits induced in rats by an amygdala depressant, Thiazesim HCl
o e o e o o o o o o o e o e o o o o e o o V 1 1 1 
1970
1970
Effects of a tranquilizer and two antidepressants on learned and unlearned behaviors.
The dose-response effects of chlorpromazine, imipramine, and thiazesim were investigated on unlearned behaviors (spontaneous… 
1969
1969
Evaluation of thiazesim (SQ 10,496) as an anti-depressant: a negative report.
1968
1968
Metabolism of thiazesim, 5-(2-dimethylaminoethyl)-2,3-dihydro-2-phenyl-1,5-benzothiazepin-4 (5H)-one, in the rat in vivo and in vitro.
Three metabolites of thiazesim, 5-(2-dimethylaminoethyl)-2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-one, were isolated from… 
1968
1968
Thiazesim (SQ-10, 496) in the treatment of depressed patients.
Highly Cited
1966
Highly Cited
1966
Effects of drugs on the mouse-killing (muricide) test and its relationship to amygdaloid function.
Review
1966
Review
1966
The effects of thiazesim, LSD-25, and bilateral lesions of the amygdalae on the release of a suppressed response.
A variety of experimental conditions can cause an animal to suppress or “control” a specific somatic response for varying time… 
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