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tetrocarcin A

Known as: antlermicin A 
 
National Institutes of Health

Papers overview

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2011
2011
l-Digitoxose is an unusual dideoxysugar found attached to various pharmacologically active natural products, including the… Expand
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Highly Cited
2008
Highly Cited
2008
Tetrocarcin A (TCA), produced by Micromonospora chalcea NRRL 11289, is a spirotetronate antibiotic with potent antitumor activity… Expand
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2007
2007
A survival kinase, Akt, is a downstream factor in the phosphatidylinositide-3'-kinase-dependent pathway, which mediates many… Expand
2001
2001
Tetrocarcin A was recently identified as an inhibitor of the anti-apoptotic function of Bcl-2. We synthesized novel tetrocarcin… Expand
Highly Cited
2000
Highly Cited
2000
Bcl-2 is an integral, intracellular membrane protein that prevents cells from undergoing apoptosis in response to a variety of… Expand
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2000
2000
Bcl-2 is an integral, intracellular membrane protein that prevents cells from undergoing apoptosis in response to a variety of… Expand
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1982
1982
Tetrocarcin A, isolated from a Micromonospora culture showed activity against experimental i.p. inoculated tumors such as Ehrlich… Expand
Highly Cited
1980
Highly Cited
1980
Novel antitumor antibiotics, tetrocarcin complex composed of three components (A, B and C) were isolated from the culture broth… Expand
1980
1980
A novel antitumor antibiotic complex has been obtained from the culture broth of Actinomycete strain DO-11 (KY11091) isolated… Expand