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tetrocarcin A
Known as:
antlermicin A
National Institutes of Health
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1 relation
Broader (1)
Aminoglycosides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Combined structural and functional investigation of a C-3''-ketoreductase involved in the biosynthesis of dTDP-L-digitoxose.
R. Kubiak
,
H. Holden
Biochemistry
2011
Corpus ID: 18301694
l-Digitoxose is an unusual dideoxysugar found attached to various pharmacologically active natural products, including the…
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2010
2010
Molecular architecture of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose.
N. Bruender
,
J. Thoden
,
M. Kaur
,
M. K. Avey
,
H. Holden
Biochemistry
2010
Corpus ID: 5289004
S-Adenosylmethionine (SAM)-dependent methyltransferases are involved in a myriad of biological processes, including signal…
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Highly Cited
2008
Highly Cited
2008
Cloning and Characterization of the Tetrocarcin A Gene Cluster from Micromonospora chalcea NRRL 11289 Reveals a Highly Conserved Strategy for Tetronate Biosynthesis in Spirotetronate Antibiotics
Jie Fang
,
Yiping Zhang
,
+5 authors
Wen Liu
Journal of Bacteriology
2008
Corpus ID: 29368366
ABSTRACT Tetrocarcin A (TCA), produced by Micromonospora chalcea NRRL 11289, is a spirotetronate antibiotic with potent antitumor…
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2007
2007
Apoptosis and inactivation of the PI3-kinase pathway by tetrocarcin A in breast cancers.
H. Nakajima
,
K. Sakaguchi
,
+4 authors
N. Mizuta
Biochemical and Biophysical Research…
2007
Corpus ID: 30537784
2001
2001
Synthesis of tetrocarcin derivatives with specific inhibitory activity towards Bcl-2 functions.
M. Kaneko
,
T. Nakashima
,
Y. Uosaki
,
M. Hara
,
S. Ikeda
,
Y. Kanda
Bioorganic & Medicinal Chemistry Letters
2001
Corpus ID: 27523155
Highly Cited
2000
Highly Cited
2000
Tetrocarcin A inhibits mitochondrial functions of Bcl-2 and suppresses its anti-apoptotic activity.
T. Nakashima
,
M. Miura
,
M. Hara
Cancer Research
2000
Corpus ID: 7915286
Bcl-2 is an integral, intracellular membrane protein that prevents cells from undergoing apoptosis in response to a variety of…
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2000
2000
Suppresses Its Anti-apoptotic Activity Tetrocarcin A Inhibits Mitochondrial Functions of Bcl-2 and Updated
T. Nakashima
,
M. Miura
,
M. Hara
2000
Corpus ID: 15543734
Bcl-2 is an integral, intracellular membrane protein that prevents cells from undergoing apoptosis in response to a variety of…
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1982
1982
Tetrocarcins, new antitumor antibiotics. 3. Antitumor activity of tetrocarcin A.
M. Morimoto
,
M. Fukui
,
S. Ohkubo
,
T. Tamaoki
,
F. Tomita
Journal of antibiotics (Tokyo. )
1982
Corpus ID: 31630879
Tetrocarcin A, isolated from a Micromonospora culture showed activity against experimental i.p. inoculated tumors such as Ehrlich…
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Highly Cited
1980
Highly Cited
1980
Tetrocarcins, novel antitumor antibiotics. II. Isolation, characterization and antitumor activity.
T. Tamaoki
,
M. Kasai
,
+5 authors
F. Tomita
Journal of antibiotics (Tokyo. )
1980
Corpus ID: 22497050
Novel antitumor antibiotics, tetrocarcin complex composed of three components (A, B and C) were isolated from the culture broth…
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1980
1980
Tetrocarcins, novel antitumor antibiotics. I. Producing organism, fermentation and antimicrobial activity.
F. Tomita
,
T. Tamaoki
Journal of antibiotics (Tokyo. )
1980
Corpus ID: 38496439
A novel antitumor antibiotic complex has been obtained from the culture broth of Actinomycete strain DO-11 (KY11091) isolated…
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