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testololactone

Known as: D-homo-17 alpha-oxaandrost-4-ene-3,17-dione, hydrotestolactone 
National Institutes of Health

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Broader (1)

Testolactone
analogs & derivatives

Papers overview

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2010
2010
Transformation of some 3α-substituted steroids by Aspergillus tamarii KITA reveals stereochemical restriction of steroid binding orientation in the minor hydroxylation pathway
2010
2010
Transformation of a series of saturated isomeric steroidal diols by Aspergillus tamarii KITA reveals a precise stereochemical requirement for entrance into the lactonization pathway
2007
2007
Distinct metabolic handling of 3beta-hydroxy-17a-oxa-D-homo-5alpha-androstan-17-one by the filamentous fungus Aspergillus tamarii KITA: Evidence in support of steroid/hydroxylase binding hypothesis.
Review
2004
Review
2004
First generation aromatase inhibitors — aminoglutethimide and testololactone
SummaryAminoglutethimide and testololactone may be considered the first generation aromatase inhibitors for the endocrine… 
1986
1986
Studies on steroid monooxygenase from Cylindrocarpon radicicola ATCC 11011. Oxygenative lactonization of androstenedione to testololactone.
A steroid monooxygenase of Cylindrocarpon radicicola was found to catalyze oxygenative lactonization of 17-ketosteroid… 
1982
1982
Estrogen synthesis in human breast tumor and its inhibition by testololactone and bromoandrostenedione.
A total of 53 tumors have been examined for estrogen synthesis from androstenedione and assayed for estradiol receptors. It was… 
1982
1982
HYDROTESTOLACTONE LOWERS SERUM OESTRADIOL AND PRL LEVELS IN NORMAL MEN: EVIDENCE OF A ROLE OF OESTRADIOL IN PRL SECRETION *
The effect on serum PRL levels of lowering serum oestradiol (E2) concentration by short‐term administration of an aromatase… 
1981
1981
Direct evidence in men for a role of endogenous oestrogens on gonadotrophin release.
In six healthy subjects serum oestradiol was selectively decreased by administering an aromatase activity inhibitor… 
1980
1980
The ultrastructure of process formation following treatment with db-cAMP of a Chinese hamster ovary x Chinese hamster brain cell hybrid.
1951
1951
The Singularly Brief Anabolic Activity of Testololactone, A Compound Lacking Androgenicity
Summary Testololactone has been demonstrated to have protein-anabolic activity, having passed both the levator ani screening test… 
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