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tesaglitazar

Known as: (2S)-2-Ethoxy-3-(4-(2-(4-((methylsulfonyl)oxy)phenyl)ethoxy)phenyl)propanoic acid, 2-ethoxy-3-(4-((4-(methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acid, (S)-2-ethoxy-3-(4-(2-(4-methylsulphonyloxyphenyl)ethoxy)phenyl)propanoic acid 
A dual peroxisome proliferator-activated receptor (PPAR) agonist, with hypoglycemic activity. Tesaglitazar is more potent on the gamma subtype than… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Peroxisome proliferator activated receptors (PPARs) α, -γ and -β/δ are ligand-activated transcription factors and members of the… Expand
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Review
2014
Review
2014
  • M. Mansour
  • Progress in molecular biology and translational…
  • 2014
  • Corpus ID: 32705187
The epidemic of obesity and its association with insulin resistance, glucose intolerance, hypertension, and dyslipidemia… Expand
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Highly Cited
2008
Highly Cited
2008
Pharmacokinetic (PK) pharmacodynamic (PD) modeling was applied to understand and quantitate the interplay between tesaglitazar (a… Expand
2007
2007
This randomised, double-blind, parallel-group, mul-ticentre study investigated the effects of the dual peroxisome proliferator… Expand
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Highly Cited
2007
Highly Cited
2007
Peroxisome proliferator–activated receptors (PPARs) are nuclear transcription factors and play a central role in insulin… Expand
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2007
2007
This randomised, double-blind, parallel-group study assessed the effects of addition of the dual peroxisome proliferator… Expand
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2006
2006
OBJECTIVE We investigated whether the dual PPARalpha/gamma agonist tesaglitazar has anti-atherogenic effects in ApoE*3Leiden mice… Expand
Highly Cited
2005
Highly Cited
2005
Aims/hypothesisInsulin resistance is associated with abnormalities in lipid and glucose metabolism, which are major components of… Expand
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Review
2005
Review
2005
There are three peroxisome proliferator-activated receptors (PPARs) subtypes which are commonly designated PPAR alpha, PPAR gamma… Expand
Highly Cited
2003
Highly Cited
2003
Although peroxisome proliferator-activated receptor (PPAR)γ agonists ameliorate insulin resistance, they sometimes cause body… Expand
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