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tesaglitazar

Known as: (2S)-2-Ethoxy-3-(4-(2-(4-((methylsulfonyl)oxy)phenyl)ethoxy)phenyl)propanoic acid, 2-ethoxy-3-(4-((4-(methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acid, (S)-2-ethoxy-3-(4-(2-(4-methylsulphonyloxyphenyl)ethoxy)phenyl)propanoic acid 
A dual peroxisome proliferator-activated receptor (PPAR) agonist, with hypoglycemic activity. Tesaglitazar is more potent on the gamma subtype than… Expand
National Institutes of Health

Papers overview

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2009
2009
BACKGROUND AND PURPOSE We have evaluated the effects of a peroxisome proliferator-activated receptor (PPAR)alpha/gamma agonist on… Expand
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2008
2008
Pharmacokinetic (PK) pharmacodynamic (PD) modeling was applied to understand and quantitate the interplay between tesaglitazar (a… Expand
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2007
2007
Peroxisome proliferator-activated receptors (PPARs) are nuclear transcription factors and play a central role in insulin… Expand
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2007
2007
This randomised, double-blind, parallel-group study assessed the effects of addition of the dual peroxisome proliferator… Expand
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2007
2007
This randomised, double-blind, parallel-group, mul-ticentre study investigated the effects of the dual peroxisome proliferator… Expand
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2007
2007
The efficacy and safety of tesaglitazar (0.5 and 1 mg) and pioglitazone (15, 30 and 45 mg) were compared in a 24-week, randomised… Expand
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2007
2007
OBJECTIVE The transcription factors, peroxisome proliferator-activated receptors (PPAR) alpha (alpha) and gamma (gamma), which… Expand
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2006
2006
OBJECTIVE We investigated whether the dual PPARalpha/gamma agonist tesaglitazar has anti-atherogenic effects in ApoE*3Leiden mice… Expand
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2005
2005
Aims/hypothesisInsulin resistance is associated with abnormalities in lipid and glucose metabolism, which are major components of… Expand
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Review
2005
Review
2005
There are three peroxisome proliferator-activated receptors (PPARs) subtypes which are commonly designated PPAR alpha, PPAR gamma… Expand
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