tenovin-6
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Sirtuin 1 (Sirt1) is a gene with diverse and complex roles in metabolic regulation, tumorigenesis and longevity, the latter being…
The developmental receptor NOTCH plays an important role in various human cancers as a consequence of oncogenic mutations. Here…
The exocrine pancreas can undergo acinar-to-ductal metaplasia (ADM), as in the case of pancreatitis where precursor lesions of…
Pharmacological activation of wild-type p53 has been found to protect normal cells in culture from cytotoxicity and nuclear…
Aim: Tenovin-6 is one of the small molecule inhibitors of Histone Deacetylase (HDAC), which have been to shown to suppress cancer…
Abstract 1542 Tenovin-6, an inhibitor for nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase Sirtuins, shows…
In spite of the low incidence of sarcomas, they are highly aggressive tumors, with high metastatic potential, and resistance to…
The p53 tumor suppressor is a critical transcription factor for controlling cell growth and apoptosis during times of cellular…