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telosome

Known as: Pot1-Tpz1 complex location, shelterin complex, shelterin complex location 
A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved… 
National Institutes of Health

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Shelterin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Protection of the shelterin complex is key for tethering telomeres to the nuclear envelope during meiotic prophase I†
Protection of the shelterin complex is key for tethering telomeres to the nuclear envelope during meiotic prophase I† Miao Li1,2… 
2018
2018
Novel combination of tanshinone I and lenalidomide induces chemo-sensitivity in myeloma cells by modulating telomerase activity and expression of shelterin complex and its associated molecules
Shelterin complex and its associated molecules are imperative for proper functioning and maintenance of human telomeres. These… 
2018
2018
Nucleolar TRF2 attenuated nucleolus stress-induced HCC cell-cycle arrest by altering rRNA synthesis
The nucleolus is an important organelle that is responsible for the biogenesis of ribosome RNA (rRNA) and ribosomal subunits… 
2017
2017
Telomere length variation and expression analysis of shelterin complex genes during gallbladder carcinogenesis
Background: Telomeres, which are bound with shelterin protein complex, play an important role in maintaining genomic stability… 
2015
2015
Minishelterins separate telomere length regulation and end protection in fission yeast
The conserved shelterin complex is critical for chromosome capping and maintaining telomere length homeostasis. Using a… 
2011
2011
Changes in the expression of telomere maintenance genes might play a role in the pathogenesis of systemic lupus erythematosus
Previous studies demonstrated that telomerase activity increased while telomere length shortened in peripheral blood mononuclear… 
2010
2010
Taking apart Rap1
Mammalian Rap1, a TRF2-interacting protein in the telomeric shelterin complex, was recently shown to repress homology-directed… 
2010
2010
Telomere Protection by TPP 1 Is Mediated by POT 1 a and POT 1 b
Mammalian telomeres are protected by the shelterin complex, which contains single-stranded telomeric DNA binding proteins (POT1a… 
2009
2009
Phosphorylation of Telomeric Repeat Binding Factor 1 (TRF1) by Akt Causes Telomere Shortening
Telomeric repeat binding factor 1 (TRF1) belongs to the shelterin complex, which modulates the telomere structures. Akt/protein… 
Highly Cited
2008
Highly Cited
2008
Role of TRF2 in the assembly of telomeric chromatin
Telomeric chromatin is composed of TTAGGG repeats bound by the shelterin complex. Mammalian telomeres also contain arrays of… 
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