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telosome
Known as:
Pot1-Tpz1 complex location
, shelterin complex
, shelterin complex location
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A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved…
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National Institutes of Health
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Related topics
Related topics
1 relation
Shelterin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract 3136: Unveiling the therapeutic potential of Tanshinone I on telomerase activity and shelterin complex in myeloma
Raman Kumar
,
R. Khan
,
N. Gupta
,
T. Seth
,
Alpana Sharma
2017
Corpus ID: 80105679
2017
2017
Structural analysis and predicting effects of natural mutations on telomerase
M. Padariya
,
U. Kalathiya
,
M. Bagiński
2017
Corpus ID: 92990959
Telomeres, the nucleoproteins ends of eukaryotic chromosomes are essential elements which stabilize chromosome ends and allow the…
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2017
2017
Molecular basis of TRF proteins and their interactions with peptides
U. Kalathiya
,
M. Padariya
,
M. Bagiński
2017
Corpus ID: 104219889
Telomeres are nucleoprotein complexes and specialized heterochromatic structures present at the ends of eukaryotic chromosomes…
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2016
2016
Investigation of Telomerase-dependent and Telomerase-independent Mechanisms of Telomere Homeostasis
Hyun-Ik Jun
2016
Corpus ID: 90364664
Author(s): Jun, Hyun-Ik | Advisor(s): Qiao, Feng | Abstract: Telomeres, the natural ends of linear eukaryotic chromosomes, are…
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2015
2015
The Role of telomere sheltrin components of telomere TRF2 and DNA damage response ATM in colorectal cancer progression in Saudi patients
Abeer M. Aldbass
,
Sooad Al-Daihan
2015
Corpus ID: 53630281
or synopsis of the proposal (200 words or less): One of the most common cancer in Saudi Arabia is colorectal cancer in which the…
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2014
2014
The interaction of ZSCAN4 with shelterin complex members: A possible role for telomere regulation in cancer cells
Kyungwoo Lee
2014
Corpus ID: 90056453
2014
2014
BONE MARROW FAILURE Bone marrow failure and the telomeropathies
D. Townsley
,
B. Dumitriu
,
N. Young
2014
Corpus ID: 11769056
Our understanding of the pathophysiology of aplastic anemia is undergoing significant revision, with implications for diagnosis…
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2014
2014
Abstract 550: Genomic instability and telomere characteristics as predictive biomarkers of therapeutic response in triple-negative breast cancer
M. Gay-Bellile
,
N. Radosevic-Robin
,
+11 authors
A. Tchirkov
2014
Corpus ID: 72958170
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Background. Triple negative breast cancers (TNBC…
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2011
2011
Molecular and Cellular Pathobiology Sirtuin 1 Is Upregulated in a Subset of Hepatocellular Carcinomas where It Is Essential for Telomere Maintenance and Tumor Cell Growth
Juan Chen
,
Bin Zhang
,
+13 authors
Ben C. B. Ko
2011
Corpus ID: 2029367
Hepatocellular carcinoma (HCC) is a highly malignant tumor with a poor prognosis. Treatment of HCC is complicated by the fact…
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2010
2010
TINF2 Mutations In Patients with Aplastic Anemia Result In Low TIN2 Expression In Hematopoietic Cells and Very Short Telomeres.
R. Calado
,
S. Savage
,
+4 authors
N. Young
2010
Corpus ID: 208382587
Abstract 1165 Telomeres, the ends of chromosomes, protect against chromosomal instability. They are composed of hundreds to…
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