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Shelterin

Known as: Shelterin Complex, Telosome 
A protein complex that is physically bound to chromosomal telomeres and plays a role in both the elongation and maintenance of telomeric repeats.
National Institutes of Health

Related topics

Related topics

10 relations
ACD protein, humanProtection of Telomeres Protein 1TERF1 protein, humanTERF2 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
How shelterin solves the telomere end-protection problem.
The symphony of the human genome concludes with a long Gregorian chant of TTAGGG repeats. This monotonous coda represents one of… 
2009
2009
Ku's essential role in keeping telomeres intact
Telomeres, the specialized nucleoprotein structures present at the ends of linear chromosomes, function to prevent natural… 
2009
2009
Developmental studies of Xenopus shelterin complexes: the message to reset telomere length is already present in the egg
The 6‐protein complex shelterin protects the telomeres of human chromosomes. The recent discovery that telomeres are important… 
Review
2005
Review
2005
Meeting report: the role of telomeres and telomerase in cancer.
The role of telomeres and telomerase in cancer is an area of much recent interest. This conference sponsored by the American… 
2004
2004
Detection of a 4DL chromosome segment translocated to rye chromosome 5R in an advanced hexaploid triticale line Bronco 90
Bronco 90 is an advanced line of hexaploid triticale and was reported to be a 2D(2R) chromosome substitution type. In F1 hybrids… 
1998
1998
Heterochromatin Organization of a Natural Yeast Telomere
We have defined the in vivoheterochromatin structure of the left telomere of Saccharomyces cerevisiae chromosome III (LIII… 
1995
1995
Extra telomeres, but not internal tracts of telomeric DNA, reduce transcriptional repression at Saccharomyces telomeres.
Yeast telomeric DNA is assembled into a nonnucleosomal chromatin structure known as the telosome, which is thought to influence… 
Highly Cited
1993
Highly Cited
1993
Oxytricha telomere-binding protein: DNA-dependent dimerization of the alpha and beta subunits.
A telomere-binding protein consisting of 56-kDa (alpha) and 41-kDa (beta) subunits binds specifically to the single-stranded… 
1991
1991
Identification of ‘Amigo’ and ‘Kavkaz’ translocations in Ohio soft red winter wheats (Triticum aestivum L.)
SummaryOne cultivar (‘GR876’) and two advanced Ohio soft red winter wheat lines (‘OH413’ and ‘OH414’), with ‘Kavkaz’ in their… 
1984
1984
Distribution of Nonstructural Variation along Three Chromosome Arms between Wheat Cultivars Chinese Spring and Cheyenne.
Metaphase I (MI) pairing of wheat homologous chromosomes is usually reduced in hybrids between cultivars relative to the parental… 
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