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telomere

Known as: Telomeres 
OBSOLETE. A complex of DNA and protein that seals the end of a chromosome. The telomeric DNA consists of simple tandemly repeated sequences specific… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Sirtuin is an essential factor that delays cellular senescence and extends the organismal lifespan through the regulation of… Expand
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Review
2019
Review
2019
Abstract Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous regarding site of origin, biological… Expand
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Review
2018
Review
2018
BackgroundTumors contain a functional subpopulation of cells that exhibit stem cell properties. These cells, named cancer stem… Expand
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Review
2018
Review
2018
In recent years, the paradigm that genomic abnormalities in cancer cells arise through progressive accumulation of mutational… Expand
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Review
2018
Review
2018
The concept of a pace-of-life syndrome describes inter- and intraspecific variation in several life-history traits along a slow… Expand
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Highly Cited
2003
Highly Cited
2003
Most human somatic cells can undergo only a limited number of population doublings in vitro. This exhaustion of proliferative… Expand
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Highly Cited
2002
Highly Cited
2002
  • R. Cawthon
  • Nucleic acids research
  • 2002
  • Corpus ID: 9299886
It has long been presumed impossible to measure telomeres in vertebrate DNA by PCR amplification with oligonucleotide primers… Expand
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Highly Cited
1992
Highly Cited
1992
When human fibroblasts from different donors are grown in vitro, only a small fraction of the variation in their finite… Expand
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Highly Cited
1990
Highly Cited
1990
THE terminus of a DNA helix has been called its Achilles' heel1. Thus to prevent possible incomplete replication2 and… Expand
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Highly Cited
1985
Highly Cited
1985
We have found a novel activity in Tetrahymena cell free extracts that adds tandem TTGGGG repeats onto synthetic telomere primers… Expand
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