telomere

Known as: Telomeres 
OBSOLETE. A complex of DNA and protein that seals the end of a chromosome. The telomeric DNA consists of simple tandemly repeated sequences specific… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Telomere length and telomerase activity are important factors in the pathobiology of human disease. Age-related diseases and… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Most human somatic cells can undergo only a limited number of population doublings in vitro. This exhaustion of proliferative… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
It has long been presumed impossible to measure telomeres in vertebrate DNA by PCR amplification with oligonucleotide primers… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Loss of telomere function can induce cell cycle arrest and apoptosis. To investigate the processes that trigger cellular… (More)
  • table 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Telomere length has frequently been used as a means to predict the future life of cells. But by itself it can be a poor indicator… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Mammalian telomeres contain a duplex array of telomeric repeats bound to the telomeric repeat-binding factors TRF1 and TRF2… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Vertebrate chromosomes terminate in variable numbers of T2AG3 nucleotide repeats. In order to study telomere repeats at… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1992
Highly Cited
1992
When human fibroblasts from different donors are grown in vitro, only a small fraction of the variation in their finite… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1990
Highly Cited
1990
THE terminus of a DNA helix has been called its Achilles' heel1. Thus to prevent possible incomplete replication2 and… (More)
Is this relevant?
Highly Cited
1985
Highly Cited
1985
We have found a novel activity in Tetrahymena cell free extracts that adds tandem TTGGGG repeats onto synthetic telomere primers… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?