telbivudine

Known as: 2'-Deoxy-L-thymidine, 1-(2-Deoxy-beta-L-ribofuranosyl)-5-methyluracil, telbivudine [Chemical/Ingredient] 
A synthetic thymidine nucleoside analogue with antiviral activity highly specific for the treatment of hepatitis B virus (HBV). Intracellularly… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2017
05010019662017

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS In the Asia-Pacific region, perinatal transmission of the hepatitis B virus (HBV) is the primary cause of… (More)
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Highly Cited
2010
Highly Cited
2010
UNLABELLED The impact of prolonged direct antiviral therapy on hepatitis B surface antigen (HBsAg) levels in patients with… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND & AIMS The GLOBE trial has compared the efficacy and safety of telbivudine versus lamivudine treatment over 2 years in… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND/AIMS In the GLOBE trial, telbivudine treatment was identified as a significant, independent predictor of better… (More)
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Highly Cited
2008
Highly Cited
2008
UNLABELLED Chronic hepatitis B and its life-threatening sequelae are highly prevalent in China. There is a need for effective new… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Reducing hepatitis B virus (HBV) replication to minimal levels is emerging as a key therapeutic goal for chronic… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The efficacy of nucleoside and nucleotide analogues for hepatitis B has been linked to the magnitude and durability of… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS A previous 4-week trial of telbivudine in patients with chronic hepatitis B indicated marked antiviral effects… (More)
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Highly Cited
1992
Highly Cited
1992
Increasingly strong evidence suggests that cholinergic neurons in the mesopontine tegmentum play important roles in the control… (More)
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Highly Cited
1990
Highly Cited
1990
This study was performed to examine the hypothesis that thalamic-projecting neurons of mesopontine cholinergic nuclei display… (More)
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