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tebipenem

National Institutes of Health

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Carbapenems

Papers overview

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2019
2019
In Vitro Activity of Tebipenem (SPR859) against Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria
Tebipenem (SPR859) is the microbiologically active form of SPR994 (tebipenem-pivoxil), an orally available carbapenem with… 
2017
2017
Ionophore A23187 shows anti-tuberculosis activity and synergy with tebipenem.
2016
2016
Solid-state stability studies of crystal form of tebipenem
Abstract The aim of this study was to determine the kinetic and thermodynamic parameters of tebipenem degradation in the solid… 
2016
2016
Investigations on yearly changes in tebipenem susceptibility of bacterial isolates from pediatric patients -A post-marketing surveillance of tebipenem pivoxil granules for pediatric.
We conducted the post-marketing surveillance of tebipenem pivoxil (Orapeneme fine granules 10% for pediatric), an oral carbapenem… 
Review
2015
Review
2015
Nationwide survey of the development of drug resistance in the pediatric field in 2007, 2010, and 2012: drug sensitivity of Haemophilus influenzae serotype b strain in Japan.
2014
2014
Extensively drug-resistant Pseudomonas aeruginosa ventriculitis and meningitis treated with intrathecal colistin.
Review
2013
Review
2013
Nationwide survey of the development of drug-resistant pathogens in the pediatric field in 2007 and 2010: drug sensitivity of Streptococcus pneumoniae in Japan (second report)
We previously conducted nationwide surveillance of Streptococcus pneumoniae in 2000–2001 (period 1) and 2004 (period 2) and… 
2013
2013
In vitro activity of tebipenem against Burkholderia pseudomallei.
2012
2012
Stress Degradation Studies of Tebipenem and a Validated Stability-Indicating LC Method
A inexpensive and rapid isocratic LC method has been developed for the quantitative determination of tebipenem—a new β-lactam… 
2012
2012
[Antibacterial susceptibility surveillance of Haemophilus influenzae isolated from pediatric patients in Gifu and Aichi prefectures (2009-2010)].
We investigated the susceptibility to antibacterial agents of 197 strains of Haemophilus influenzae isolated from pediatric… 
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