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tebipenem

National Institutes of Health

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Carbapenems

Papers overview

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2020
2020
In Vitro and In Vivo Characterization of Tebipenem, an Oral Carbapenem
The continued evolution of bacterial resistance to the β-lactam class of antibiotics has necessitated countermeasures to ensure… 
2019
2019
Genetic characteristics and antibiotic resistance of Haemophilus influenzae isolates from pediatric patients with acute otitis media after introduction of 13-valent pneumococcal conjugate vaccine in…
2019
2019
In Vitro Activity of Tebipenem (SPR859) against Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria
Tebipenem (SPR859) is the microbiologically active form of SPR994 (tebipenem-pivoxil), an orally available carbapenem with… 
2017
2017
Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem
BackgroundThe carbapenem subclass of β-lactams is among the most potent antibiotics available today. Emerging evidence shows that… 
2017
2017
Antimicrobial susceptibility testing of rapidly growing mycobacteria isolated in Japan
BackgroundDifficult-to-treat infections caused by rapidly growing mycobacteria (RGM) are increasingly observed in clinical… 
2017
2017
In vitro efficacy of 16 antimicrobial drugs against a large collection of &bgr;‐lactamase‐producing isolates of extraintestinal pathogenic Escherichia coli from dogs and cats
Purpose. The aim of this study was to assess the in vitro efficacy of candidate antimicrobials against extended‐spectrum &bgr… 
2016
2016
Solid-state stability studies of crystal form of tebipenem
Abstract The aim of this study was to determine the kinetic and thermodynamic parameters of tebipenem degradation in the solid… 
Review
2015
Review
2015
Nationwide survey of the development of drug resistance in the pediatric field in 2000-2001, 2004, 2007, 2010, and 2012: evaluation of the changes in drug sensitivity of Haemophilus influenzae and…
2014
2014
Extensively drug-resistant Pseudomonas aeruginosa ventriculitis and meningitis treated with intrathecal colistin.
2012
2012
Stress Degradation Studies of Tebipenem and a Validated Stability-Indicating LC Method
A inexpensive and rapid isocratic LC method has been developed for the quantitative determination of tebipenem—a new β-lactam… 
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