Skip to search formSkip to main contentSkip to account menu

taspine

Known as: thaspine 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Alkaloids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Novel compounds TAD-1822-7-F2 and F5 inhibited HeLa cells growth through the JAK/Stat signaling pathway.
2014
2014
A novel taspine derivative, HMQ1611, suppresses adhesion, migration and invasion of ZR-75-30 human breast cancer cells
BackgroundTaspine was screened for the first time from Radix et Rhizoma leonticis (Hong Mao Qi in Chinese) using cell membrane… 
2012
2012
A Novel Taspine Derivative, HMQ1611, Inhibits Breast Cancer Cell Growth via Estrogen Receptor α and EGF Receptor Signaling Pathways
Breast cancer is a common cancer with a leading cause of cancer mortality in women. Currently, the chemotherapy for breast cancer… 
2012
2012
A novel taspine analog, HMQ1611, inhibits growth of non-small cell lung cancer by inhibiting angiogenesis.
In the present study, we investigated the antitumor activity of HMQ1611, a novel synthetic taspine derivative, in vivo and… 
2011
2011
Antitumor Activity of Taspine by Modulating the EGFR Signaling Pathway of Erk1/2 and Akt In Vitro and In Vivo
in vivo 
Review
2011
Review
2011
Synthesis and cytotoxic evaluation of novel symmetrical taspine derivatives as anticancer agents.
It has been demonstrated that taspine derivatives act as anticancer agents, thus we designed and synthesized a novel class of… 
2010
2010
Effects of taspine on proliferation and apoptosis by regulating caspase‐3 expression and the ratio of Bax/Bcl‐2 in A431 cells
Taspine is an active component isolated from Radix et Rhizoma Leonticis. It has been shown that taspine can inhibit tumour… 
2010
2010
Discovery of novel taspine derivatives as antiangiogenic agents.
2009
2009
Identification of a Novel Topoisomerase Inhibitor Effective in Cells Overexpressing Drug Efflux Transporters
Background Natural product structures have high chemical diversity and are attractive as lead structures for discovery of new… 
2007
2007
[Inhibitory effect of taspine on mouse S180 sarcoma and its mechanism].
OBJECTIVE To study the inhibition effect of taspine on mouse S180 sarcoma and its mechanism. METHOD The mouse S180 sarcoma… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)