tamiphosphor

Influenza neuraminidase is responsible for the escape of new viral particles from the infected cell surface. Several… (More)

 

Influenza virus causes severe respiratory infections that are responsible for up to half a million deaths worldwide each year… (More)

Oseltamivir is a potent neuraminidase inhibitor for influenza treatment. By replacing the carboxylate group in oseltamivir with… (More)

Using N-acetyl-D-glucosamine as a starting material, the anti-influenza drugs oseltamivir and tamiphosphor were synthesized via a… (More)

Oseltamivir phosphonic acid (tamiphosphor, 3a), its monoethyl ester (3c), guanidino-tamiphosphor (4a), and its monoethyl ester… (More)

We describe the synthesis of mimetics of the alpha2-3 and alpha2-6 sialogalactoside substrates of influenza neuraminidase which… (More)

the treatment of influenza, is an orally administrated prodrug which is readily hydrolyzed by hepatic esterases to give the… (More)

Influenza remains a major health problem for humans and animals. 1 At present, four drugs are approved for influenza prophylaxis… (More)