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tamiphosphor

Known as: oseltamivir phosphonic acid 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

OseltamivirPhosphorous Acids
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Discovery of Potent Neuraminidase Inhibitors Using a Combination of Pharmacophore-Based Virtual Screening and Molecular Simulation Approach
Neuraminidase (NA), a surface protein, facilitates the release of nascent virus and thus spreads infection. It has been renowned… 
2018
2018
DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors
Influenza neuraminidase is responsible for the escape of new viral particles from the infected cell surface. Several… 
2017
2017
Discovery of Potent Neuraminidase Inhibitors Using a Combination of Pharmacophore-Based Virtual Screening and Molecular Simulation Approach
  • R. K, S. V
  • Applied Biochemistry and Biotechnology
  • 2017
  • Corpus ID: 4594277
Neuraminidase (NA), a surface protein, facilitates the release of nascent virus and thus spreads infection. It has been renowned… 
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2016
2016
Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza.
Influenza virus causes severe respiratory infections that are responsible for up to half a million deaths worldwide each year… 
2014
2014
Tamiphosphor monoesters as effective anti-influenza agents.
Oseltamivir is a potent neuraminidase inhibitor for influenza treatment. By replacing the carboxylate group in oseltamivir with… 
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2013
2013
Synthesis of oseltamivir and tamiphosphor from N-acetyl-D-glucosamine.
Using N-acetyl-D-glucosamine as a starting material, the anti-influenza drugs oseltamivir and tamiphosphor were synthesized via a… 
2012
2012
Development of oseltamivir phosphonate congeners as anti-influenza agents.
Oseltamivir phosphonic acid (tamiphosphor, 3a), its monoethyl ester (3c), guanidino-tamiphosphor (4a), and its monoethyl ester… 
2009
2009
Galactose-conjugates of the oseltamivir pharmacophore--new tools for the characterization of influenza virus neuraminidases.
We describe the synthesis of mimetics of the alpha2-3 and alpha2-6 sialogalactoside substrates of influenza neuraminidase which… 
Highly Cited
2008
Highly Cited
2008
A concise and flexible synthesis of the potent anti-influenza agents tamiflu and tamiphosphor.
We report safer and more commercially viable synthetic methods for both antiinfluenza drugs Tamiflu and Tamiphosphor using… 
Highly Cited
2007
Highly Cited
2007
Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity.
Using d-xylose as an appropriate chiral precursor, we have synthesized active neuraminidase inhibitor oseltamivir, antiflu drug… 
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