tamiphosphor

Neuraminidase (NA), a surface protein, facilitates the release of nascent virus and thus spreads infection. It has been renowned… Expand

Influenza neuraminidase is responsible for the escape of new viral particles from the infected cell surface. Several… Expand

Neuraminidase (NA), a surface protein, facilitates the release of nascent virus and thus spreads infection. It has been renowned… Expand

Influenza virus causes severe respiratory infections that are responsible for up to half a million deaths worldwide each year… Expand

Oseltamivir is a potent neuraminidase inhibitor for influenza treatment. By replacing the carboxylate group in oseltamivir with… Expand

Using N-acetyl-D-glucosamine as a starting material, the anti-influenza drugs oseltamivir and tamiphosphor were synthesized via a… Expand

Oseltamivir phosphonic acid (tamiphosphor, 3a), its monoethyl ester (3c), guanidino-tamiphosphor (4a), and its monoethyl ester… Expand

We describe the synthesis of mimetics of the alpha2-3 and alpha2-6 sialogalactoside substrates of influenza neuraminidase which… Expand

We report safer and more commercially viable synthetic methods for both antiinfluenza drugs Tamiflu and Tamiphosphor using… Expand

Using d-xylose as an appropriate chiral precursor, we have synthesized active neuraminidase inhibitor oseltamivir, antiflu drug… Expand