FAQ

t(6;9)

A cytogenetic abnormality that involves a translocation between chromosomes 6 and 9.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1983-2016
024619832016

Related topics

Related topics

2 relations
Chromosomes, Human, Pair 6Chromosomes, Human, Pair 9

Related mentions per year

Related mentions per year

1942-2018
19401960198020002020
t(6;9)
Chromosomes, Human, Pair 6
Chromosomes, Human, Pair 9

Papers overview

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2016
2016
Novel MYBL1 Gene Rearrangements with Recurrent MYBL1-NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations.
PURPOSE Adenoid cystic carcinoma (ACC) is an indolent salivary gland malignancy, characterized by t(6;9) translocations and MYB… (More)
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2011
2011
Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome.
OBJECTIVE To investigate the molecular genetic heterogeneity associated with the t(6:9) in adenoid cystic carcinoma (ACC) and… (More)
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2010
2010
The t(6;9)(p22;q34) in myeloid neoplasms: a retrospective study of 16 cases.
Among patients with acute myeloid leukemia (AML), the t(6;9) (p22;q34) is a rare but defined subset with a poor prognosis. We… (More)
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2006
2006
A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare ‘poor prognosis’ myeloid malignancies
t(6;9)(p23;q34) is a rare recurring cytogenetic aberration resulting in the formation of a chimeric DEK/NUP214 (formerly DEK/CAN… (More)
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2004
2004
Acute myeloid leukemia with t(6;9)(p23;q34) is associated with dysplasia and a high frequency of flt3 gene mutations.
We report 12 cases of t(6;9)(p23;q34)-positive acute myeloid leukemia (AML), all classified using the criteria of the World… (More)
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Highly Cited
2002
Highly Cited
2002
Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis.
Constitutive activation of the FLT3 receptor tyrosine kinase, either by internal tandem duplication (ITD) of the juxtamembrane… (More)
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Highly Cited
1992
Highly Cited
1992
The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can…
The translocation (6;9) is associated with a specific subtype of acute myeloid leukemia (AML). Previously, it was found that… (More)
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Highly Cited
1992
Highly Cited
1992
Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.
The translocation (6;9)(p23;q34) in acute nonlymphocytic leukemia results in the formation of a highly consistent dek-can fusion… (More)
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1986
1986
High resolution banding analysis of the reciprocal translocation t(6;9) in acute nonlymphocytic leukemia.
The cytogenetic, hematologic, and clinical characteristics of a 13-year-old girl with acquired t(6;9)(p23;q34) and… (More)
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1985
1985
Increased numbers of marrow basophils may be associated with a t(6;9) in ANLL.
We have characterized another subset of acute nonlymphocytic leukemia (ANLL) based on the cytogenetic and morphologic findings in… (More)
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