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t(6;9)

A cytogenetic abnormality that involves a translocation between chromosomes 6 and 9.
National Institutes of Health

Related topics

Related topics

2 relations
Chromosomes, Human, Pair 6Chromosomes, Human, Pair 9

Papers overview

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Highly Cited
2015
Highly Cited
2015
Novel MYBL1 Gene Rearrangements with Recurrent MYBL1–NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations
Purpose: Adenoid cystic carcinoma (ACC) is an indolent salivary gland malignancy, characterized by t(6;9) translocations and MYB… Expand
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2014
2014
MYB gene abnormalities t(6;9) in adenoid cystic carcinoma fine-needle aspiration biopsy using fluorescence in situ hybridization.
CONTEXT Fine-needle aspiration (FNA) biopsy of salivary gland neoplasms can have a variety of overlapping appearances. Basaloid… Expand
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Highly Cited
2011
Highly Cited
2011
Novel Chromosomal Rearrangements and Break Points at the t(6;9) in Salivary Adenoid Cystic Carcinoma: Association with MYB–NFIB Chimeric Fusion, MYB Expression, and Clinical Outcome
Objective: To investigate the molecular genetic heterogeneity associated with the t(6:9) in adenoid cystic carcinoma (ACC) and… Expand
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Highly Cited
2002
Highly Cited
2002
Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis.
Constitutive activation of the FLT3 receptor tyrosine kinase, either by internal tandem duplication (ITD) of the juxtamembrane… Expand
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Highly Cited
1997
Highly Cited
1997
Acute myeloid leukemia with t(6;9) (p23;q34): association with myelodysplasia, basophilia, and initial CD34 negative immunophenotype.
The translocation (6;9)(p23;q34) is a rare cytogenetic aberration found in patients with acute myeloid leukemia (AML). The… Expand
Highly Cited
1992
Highly Cited
1992
The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can…
The translocation (6;9) is associated with a specific subtype of acute myeloid leukemia (AML). Previously, it was found that… Expand
Highly Cited
1992
Highly Cited
1992
Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.
The translocation (6;9)(p23;q34) in acute nonlymphocytic leukemia results in the formation of a highly consistent dek-can fusion… Expand
Highly Cited
1990
Highly Cited
1990
The (6;9) chromosome translocation, associated with a specific subtype of acute nonlymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34.
The specific (6;9)(p23;q34) chromosomal translocation is associated with a defined subtype of acute nonlymphocytic leukemia (ANLL… Expand
Highly Cited
1989
Highly Cited
1989
Cytogenetics of childhood acute nonlymphocytic leukemia.
Interest in more precise subclassification of the acute leukemias by cytogenetic criteria led us to identify and characterize the… Expand
Highly Cited
1985
Highly Cited
1985
Increased numbers of marrow basophils may be associated with a t(6;9) in ANLL
We have characterized another subset of acute nonlymphocytic leukemia (ANLL) based on the cytogenetic and morphologic findings in… Expand
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