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t(6;11)

A cytogenetic abnormality that involves a translocation between chromosomes 6 and 11.
National Institutes of Health

Related topics

Related topics

2 relations
Chromosomes, Human, Pair 11Chromosomes, Human, Pair 6

Papers overview

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Review
2013
Review
2013
Review of renal carcinoma with t(6;11)(p21;q12) with focus on clinical and pathobiological aspects.
Recently, a new category of MiTF/TFE family translocation carcinomas of the kidney has been proposed. This category includes Xp11… 
Review
1998
Review
1998
ALL1 gene alterations in acute leukemia: biological and clinical aspects.
BACKGROUND AND OBJECTIVE The ALL1 gene, also referred to as MLL, HRX or Htrx1, is interrupted in the vast majority of… 
Highly Cited
1998
Highly Cited
1998
General Report on the European Union Concerted Action Workshop on 11q23, London, UK, May 1997
Seventeen cytogenetic laboratories in eight European countries contributed karyotypic, hematological, clinical and follow-up data… 
1997
1997
Chimeric MLL products with a Ras binding cytoplasmic protein AF6 involved in t(6;11) (q27;q23) leukemia localize in the nucleus
In infantile leukemias and therapy-related leukemias, the MLL gene is frequently found to be disrupted and fused to various… 
1996
1996
Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML‐2 cell line
The t(6;11)(q27;q23) is one of the most common translocations observed in patients with acute myeloid leukemia (AML). The… 
Highly Cited
1992
Highly Cited
1992
The der(II) chromosome contains the critical breakpoint junction in the 4;11, 9;11, and 11;19 translocations in acute leukemia
Translocations involving 11q23 are recurring abnormalities in human acute leukemia cells of either lymphoid or myeloid lineage… 
1992
1992
Chromosome 11q23 translocations in both infant and adult acute leukemias are detected by in situ hybridization with a yeast artificial chromosome.
The yeast artificial chromosome (YAC-13HH4), which spans a 440-kb region of DNA just distal to the CD3 locus on chromosome 11 at… 
1992
1992
An altered 11-kilobase transcript in leukemic cell lines with the t(4;11)(q21;q23) chromosome translocation.
The 11q23 chromosome band is frequently associated with chromosomal aberrations in human leukemias. We have previously cloned a… 
1991
1991
Gene mapping by microdissection and enzymatic amplification: Heterogeneity in leukaemia associated breakpoints on chromosome II
A new strategy for mapping chromosome translocation breakpoints in relation to known genes has been developed. This approach is… 
1990
1990
In situ hybridization ascertains the presence of a translocation t(6;11) in an acute monocytic leukemia
In situ hybridization was performed in a case of acute monoblastic leukemia (FAB type M5b) with a rearrangement of the long arm… 
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