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syndecan 1 protein

Known as: Antigen CD138, CD138 Antigen, Syndecan-1 
Syndecan-1 (310 aa, ~32 kDa) is encoded by the human SDC1 gene. This protein is involved in the mediation of cell adhesion, signaling and… 
National Institutes of Health

Related topics

Related topics

20 relations
CD138 Ag:PrThr:Pt:Tiss:Ord:Immune stainCell AdhesionCell-Matrix JunctionClusters of differentiation

Broader (1)

SDC1 wt Allele

Papers overview

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Highly Cited
2007
Highly Cited
2007
Juvenile syndecan-1 null mice are protected from carcinogen-induced tumor development
We previously showed that mice with a null mutation in syndecan-1 (Sdc1; CD138) were resistant to Wnt1-induced mammary tumor… 
Highly Cited
2002
Highly Cited
2002
Syndecan-2 Mediates Adhesion and Proliferation of Colon Carcinoma Cells*
Syndecan-2 is a transmembrane heparan sulfate proteoglycan whose function at the cell surface is unclear. In this study, we… 
Highly Cited
2000
Highly Cited
2000
Syndecan-2 Is Involved in the Mitogenic Activity and Signaling of Granulocyte-Macrophage Colony-stimulating Factor in Osteoblasts*
We previously showed that granulocyte-macrophage colony-stimulating factor (GM-CSF) binds to heparan sulfate proteoglycans… 
Review
1999
Review
1999
Heparin, cell adhesion, and pathogenesis of inflammatory bow el disease
Highly Cited
1999
Highly Cited
1999
Changes in the expression of syndecan-1 in the colorectal adenoma–carcinoma sequence
Abstract Syndecan-1, a transmembrane heparan sulphate proteoglycan (HSPG), functions as a matrix receptor on the basal surface of… 
Highly Cited
1998
Highly Cited
1998
Syndecan-1 expression on malignant cells from the blood and marrow of patients with plasma cell proliferative disorders and B-cell chronic lymphocytic leukemia.
Syndecan-1 is a low-affinity receptor for basic fibroblast growth factor (bFGF). In this study, we used flow cytometry to examine… 
Highly Cited
1995
Highly Cited
1995
Heparan Sulfate-mediated Cell Aggregation
Because syndecans are present at sites of cell-cell contact in vivo it has been hypothesized that they play a role in mediating… 
Highly Cited
1994
Highly Cited
1994
Immunohistochemical localization of syndecan‐1 in normal and pathological human uterine cervix
Expression of syndecan‐1, a cell surface proteoglycan that binds growth factors and extracellular matrix components, was studied… 
Highly Cited
1994
Highly Cited
1994
Aggregation-induced association of syndecan-1 with microfilaments mediated by the cytoplasmic domain.
Expression of the transmembrane proteoglycan syndecan-1 in Schwann cells leads to enhanced spreading and cytoskeletal… 
Highly Cited
1994
Highly Cited
1994
Expression of syndecan-1 is induced by differentiation and suppressed by malignant transformation of human keratinocytes.
Syndecans comprise a family of integral membrane proteoglycans that presumably participate in cell-matrix interactions and the… 
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