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syndecan 1 protein

Known as: Antigen CD138, CD138 Antigen, Syndecan-1 
Syndecan-1 (310 aa, ~32 kDa) is encoded by the human SDC1 gene. This protein is involved in the mediation of cell adhesion, signaling and… 
National Institutes of Health

Related topics

Related topics

20 relations
CD138 Ag:PrThr:Pt:Tiss:Ord:Immune stainCell AdhesionCell-Matrix JunctionClusters of differentiation

Broader (1)

SDC1 wt Allele

Papers overview

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Highly Cited
2011
Highly Cited
2011
A High Admission Syndecan-1 Level, A Marker of Endothelial Glycocalyx Degradation, Is Associated With Inflammation, Protein C Depletion, Fibrinolysis, and Increased Mortality in Trauma Patients
Objective: To investigate the association between markers of acute endothelial glycocalyx degradation, inflammation, coagulopathy… 
Highly Cited
2009
Highly Cited
2009
Syndecan-1 regulates αvβ3 and αvβ5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor
Syndecan-1 (Sdc1) is a matrix receptor shown to associate via its extracellular domain with the αvβ3 and αvβ5 integrins… 
Highly Cited
2006
Highly Cited
2006
The shedding of syndecan-4 and syndecan-1 from HeLa cells and human primary macrophages is accelerated by SDF-1/CXCL12 and mediated by the matrix metalloproteinase-9.
We recently demonstrated that stromal cell-derived factor-1 (SDF-1/CXCL12) forms complexes with CXCR4, but also with syndecan-4… 
Highly Cited
2006
Highly Cited
2006
Bmc Microbiology
A novel surface protein of Trichomonas vaginalis is regulated independently by low iron and contact with vaginal epithelial cells… 
Highly Cited
2002
Highly Cited
2002
Matrilysin Shedding of Syndecan-1 Regulates Chemokine Mobilization and Transepithelial Efflux of Neutrophils in Acute Lung Injury
Highly Cited
2002
Highly Cited
2002
Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse
Mice lacking syndecan-1 are viable, fertile and have morphologically normal skin, hair and ocular surface epithelia. While… 
Highly Cited
2000
Highly Cited
2000
Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice
Syndecan-1 is a cell-surface, heparan-sulphate proteoglycan (HSPG) predominantly expressed by epithelial cells. It binds… 
Highly Cited
2000
Highly Cited
2000
Shedding of Syndecan-1 and -4 Ectodomains Is Regulated by Multiple Signaling Pathways and Mediated by a Timp-3–Sensitive Metalloproteinase
The syndecan family of four transmembrane heparan sulfate proteoglycans binds a variety of soluble and insoluble extracellular… 
Highly Cited
1995
Highly Cited
1995
Expression of proteoglycans and hyaluronan during wound healing.
We investigated the expression of proteoglycans (PGs) and hyaluronan (HA) during healing of human mucosal wounds. Biopsy… 
Highly Cited
1994
Highly Cited
1994
Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds.
Cell surface heparan sulfate proteoglycans, such as the syndecans, are required for cellular responses to heparin-binding growth… 
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