synaptic vesicle priming

A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
0246820012017

Papers overview

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Highly Cited
2014
Highly Cited
2014
Synaptic vesicle docking, priming, and fusion at active zones are orchestrated by a complex molecular machinery. We employed… (More)
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2010
2010
Neurotransmitter release proceeds by Ca(2+)-triggered, SNARE-complex-dependent synaptic vesicle fusion. After fusion, the ATPase… (More)
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Highly Cited
2009
Highly Cited
2009
Munc18-1 and soluble NSF attachment protein receptors (SNAREs) are critical for synaptic vesicle fusion. Munc18-1 binds to the… (More)
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Highly Cited
2007
Highly Cited
2007
Before transmitter-filled synaptic vesicles can fuse with the plasma membrane upon stimulation they have to be primed to fusion… (More)
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Highly Cited
2006
Highly Cited
2006
Caenorhabditis elegans TOM-1 is orthologous to vertebrate tomosyn, a cytosolic syntaxin-binding protein implicated in the… (More)
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Highly Cited
2006
Highly Cited
2006
Priming of synaptic vesicles (SVs) is essential for synaptic transmission. UNC-13 proteins are required for priming. Current… (More)
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Highly Cited
2004
Highly Cited
2004
The efficacy of synaptic transmission between neurons can be altered transiently during neuronal network activity. This… (More)
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Highly Cited
2003
Highly Cited
2003
Second messenger cascades involving G proteins and calcium are known to modulate neurotransmitter release. A prominent effect of… (More)
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Highly Cited
2002
Highly Cited
2002
Munc13-1 is a presynaptic protein with an essential role in synaptic vesicle priming. It contains a diacylglycerol (DAG)/beta… (More)
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Highly Cited
2001
Highly Cited
2001
The priming step of synaptic vesicle exocytosis is thought to require the formation of the SNARE complex, which comprises the… (More)
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