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surface enhanced laser desorption ionization

Known as: SELDI 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Mass SpectrometrySpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Papers overview

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Highly Cited
2006
Highly Cited
2006
Identification of parotid salivary biomarkers in Sjogren's syndrome by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry and two-dimensional difference gel electrophoresis…
OBJECTIVES To identify the most significant salivary biomarkers in Sjögren's syndrome (SS) using proteomic methods. METHODS… Expand
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Highly Cited
2005
Highly Cited
2005
Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility.
BACKGROUND Protein expression profiling for differences indicative of early cancer has promise for improving diagnostics. This… Expand
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Highly Cited
2005
Highly Cited
2005
Discovery of new rheumatoid arthritis biomarkers using the surface-enhanced laser desorption/ionization time-of-flight mass spectrometry ProteinChip approach.
OBJECTIVE To identify serum protein biomarkers specific for rheumatoid arthritis (RA), using surface-enhanced laser desorption… Expand
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Highly Cited
2005
Highly Cited
2005
Enhancement of sensitivity and resolution of surface-enhanced laser desorption/ionization time-of-flight mass spectrometric records for serum peptides using time-series analysis techniques.
BACKGROUND Measurement of peptide/protein concentrations in biological samples for biomarker discovery commonly uses high… Expand
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Highly Cited
2004
Highly Cited
2004
Urine protein profiling with surface-enhanced laser-desorption/ionization time-of-flight mass spectrometry.
BACKGROUND In the last few years there has been an increasing interest in exploring the human proteome. In particular, efforts… Expand
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Highly Cited
2004
Highly Cited
2004
Serum Diagnosis of Pancreatic Adenocarcinoma Using Surface-Enhanced Laser Desorption and Ionization Mass Spectrometry
Purpose: Each year in the United States, ∼ 30,000 people die from pancreatic cancer. Fewer than 5% of patients survive >5 years… Expand
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Highly Cited
2004
Highly Cited
2004
Mass spectrometry for the detection of differentially expressed proteins: a comparison of surface-enhanced laser desorption/ionization and capillary electrophoresis/mass spectrometry.
The discovery of biomarkers is currently attracting much interest as it harbors great potential for the diagnosis and monitoring… Expand
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Highly Cited
2004
Highly Cited
2004
Artificial Neural Networks Analysis of Surface-Enhanced Laser Desorption/Ionization Mass Spectra of Serum Protein Pattern Distinguishes Colorectal Cancer from Healthy Population
Purpose: The low specificity and sensitivity of the carcinoembryonic antigen test makes it not an ideal biomarker for the… Expand
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Highly Cited
2002
Highly Cited
2002
Boosted decision tree analysis of surface-enhanced laser desorption/ionization mass spectral serum profiles discriminates prostate cancer from noncancer patients.
BACKGROUND The low specificity of the prostate-specific antigen (PSA) test makes it a poor biomarker for early detection of… Expand
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Highly Cited
1999
Highly Cited
1999
Proteinchip® surface enhanced laser desorption/ionization (SELDI) mass spectrometry: a novel protein biochip technology for detection of prostate cancer biomarkers in complex protein mixtures
Improving early detection, diagnosis, treatment monitoring and prognosis of cancer will require rapid and high throughput… Expand
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