Skip to search formSkip to main contentSkip to account menu

styrylquinoline

National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Quinolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases.
(E)-6-Methyl-4'-amino-2-styrylquinoline (3) is a small molecule with the proper features to potentially diagnose, deliver therapy… 
Review
2010
Review
2010
Chemistry and Structure-Activity Relationship of the Styrylquinoline-Type HIV Integrase Inhibitors
In spite of significant progress in anti-HIV-1 therapy, current antiviral chemo-therapy still suffers from deleterious side… 
Highly Cited
2005
Highly Cited
2005
New HIV-1 replication inhibitors of the styryquinoline class bearing aroyl/acyl groups at the C-7 position: synthesis and biological activity.
Highly Cited
2004
Highly Cited
2004
Mechanism of HIV-1 integrase inhibition by styrylquinoline derivatives in vitro.
Styrylquinoline derivatives (SQ) efficiently inhibit the 3'-processing activity of integrase (IN) with IC50 values of between 0.5… 
Highly Cited
2004
Highly Cited
2004
Nuclear Import of HIV-1 Integrase Is Inhibited in Vitro by Styrylquinoline Derivatives
Nuclear import of HIV-1 preintegration complexes (PICs) allows the virus to infect nondividing cells. Integrase (IN), the PIC… 
2004
2004
Exploring binding mode for styrylquinoline HIV-1 integrase inhibitors using comparative molecular field analysis and docking studies.
AIM To understand pharmacophore properties of styrylquinoline derivatives and to design inhibitors of HIV-1 integrase. METHODS… 
Highly Cited
2002
Highly Cited
2002
Use of the Kohonen neural network for rapid screening of ex vivo anti-HIV activity of styrylquinolines.
Using the Kohonen neural network, the electrostatic potentials on the molecular surfaces of 14 styrylquinoline derivatives were… 
Highly Cited
2000
Highly Cited
2000
Structure-activity relationships and binding mode of styrylquinolines as potent inhibitors of HIV-1 integrase and replication of HIV-1 in cell culture.
Our prior studies showed that polyhydroxylated styrylquinolines are potent HIV-1 integrase (IN) inhibitors that block the… 
Highly Cited
2000
Highly Cited
2000
Modeling of the inhibition of retroviral integrases by styrylquinoline derivatives.
Styrylquinoline derivatives, known to be potent inhibitors of HIV-1 integrase, have been experimentally tested for their… 
Highly Cited
1948
Highly Cited
1948
The fermentation of cellulose in vitro by organisms from the rumen of sheep.
The suggestion that micro-organisms are responsible for the decomposition of cellulose in the alimentary canal (Wildt, 1874… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)