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styrylquinoline

 
National Institutes of Health

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Quinolines

Papers overview

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2015
2015
Design, Synthesis and In Vitro Activity of Anticancer Styrylquinolines. The p53 Independent Mechanism of Action
A group of styrylquinolines were synthesized and tested for their anti-proliferative activity. Anti-proliferative activity was… Expand
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Highly Cited
2010
Highly Cited
2010
Synthesis and antiproliferative evaluations of certain 2-phenylvinylquinoline (2-styrylquinoline) and 2-furanylvinylquinoline derivatives.
The present study describes the synthesis of 2-phenylvinylquinoline (styrylquinoline) and 2-furanylvinylquinoline derivatives and… Expand
2008
2008
Exploring molecular shape analysis of styrylquinoline derivatives as HIV-1 integrase inhibitors.
HIV-1 integrase inhibitory activity data of styrylquinoline derivatives have been subjected to 3D-QSAR study by molecular shape… Expand
Highly Cited
2004
Highly Cited
2004
Mechanism of HIV-1 integrase inhibition by styrylquinoline derivatives in vitro.
Styrylquinoline derivatives (SQ) efficiently inhibit the 3'-processing activity of integrase (IN) with IC50 values of between 0.5… Expand
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Highly Cited
2004
Highly Cited
2004
Nuclear Import of HIV-1 Integrase Is Inhibited in Vitro by Styrylquinoline Derivatives
Nuclear import of HIV-1 preintegration complexes (PICs) allows the virus to infect nondividing cells. Integrase (IN), the PIC… Expand
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Highly Cited
2002
Highly Cited
2002
Use of the Kohonen neural network for rapid screening of ex vivo anti-HIV activity of styrylquinolines.
Using the Kohonen neural network, the electrostatic potentials on the molecular surfaces of 14 styrylquinoline derivatives were… Expand
Highly Cited
2000
Highly Cited
2000
Structure-activity relationships and binding mode of styrylquinolines as potent inhibitors of HIV-1 integrase and replication of HIV-1 in cell culture.
Our prior studies showed that polyhydroxylated styrylquinolines are potent HIV-1 integrase (IN) inhibitors that block the… Expand
Highly Cited
2000
Highly Cited
2000
Modeling of the inhibition of retroviral integrases by styrylquinoline derivatives.
Styrylquinoline derivatives, known to be potent inhibitors of HIV-1 integrase, have been experimentally tested for their… Expand
Highly Cited
1998
Highly Cited
1998
Styrylquinoline derivatives: a new class of potent HIV-1 integrase inhibitors that block HIV-1 replication in CEM cells.
On the basis of the fact that several polynucleotidyl transferases, related to HIV integrase, contain in their active site two… Expand
Highly Cited
1948
Highly Cited
1948
The fermentation of cellulose in vitro by organisms from the rumen of sheep.
  • H. Marston
  • The Biochemical journal
  • 1948
    • Corpus ID: 13635179
The suggestion that micro-organisms are responsible for the decomposition of cellulose in the alimentary canal (Wildt, 1874… Expand
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