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styrylquinoline

 

Topic mentions per year

Topic mentions per year

1958-2016
02419582016

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1 relation

Broader (1)

Quinolines

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
styrylquinoline
Quinolines

Papers overview

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2015
2015
Design, Synthesis and In Vitro Activity of Anticancer Styrylquinolines. The p53 Independent Mechanism of Action.
A group of styrylquinolines were synthesized and tested for their anti-proliferative activity. Anti-proliferative activity was… (More)
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2010
2010
Synthesis and antiproliferative evaluations of certain 2-phenylvinylquinoline (2-styrylquinoline) and 2-furanylvinylquinoline derivatives.
The present study describes the synthesis of 2-phenylvinylquinoline (styrylquinoline) and 2-furanylvinylquinoline derivatives and… (More)
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2008
2008
Exploring molecular shape analysis of styrylquinoline derivatives as HIV-1 integrase inhibitors.
HIV-1 integrase inhibitory activity data of styrylquinoline derivatives have been subjected to 3D-QSAR study by molecular shape… (More)
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2004
2004
Mechanism of HIV-1 integrase inhibition by styrylquinoline derivatives in vitro.
Styrylquinoline derivatives (SQ) efficiently inhibit the 3'-processing activity of integrase (IN) with IC50 values of between 0.5… (More)
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2004
2004
Nuclear import of HIV-1 integrase is inhibited in vitro by styrylquinoline derivatives.
Nuclear import of HIV-1 preintegration complexes (PICs) allows the virus to infect nondividing cells. Integrase (IN), the PIC… (More)
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2004
2004
Exploring binding mode for styrylquinoline HIV-1 integrase inhibitors using comparative molecular field analysis and docking studies.
AIM To understand pharmacophore properties of styrylquinoline derivatives and to design inhibitors of HIV-1 integrase. METHODS… (More)
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2003
2003
Synthesis of styrylbenzofuran derivatives as styrylquinoline analogues for HIV-1 integrase inhibitor.
A series of styrylbenzofuran derivatives (8a-i) as styrylquinoline isosters were efficiently prepared by Wittig reaction and… (More)
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2002
2002
Use of the Kohonen neural network for rapid screening of ex vivo anti-HIV activity of styrylquinolines.
Using the Kohonen neural network, the electrostatic potentials on the molecular surfaces of 14 styrylquinoline derivatives were… (More)
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2000
2000
Structure-activity relationships and binding mode of styrylquinolines as potent inhibitors of HIV-1 integrase and replication of HIV-1 in cell culture.
Our prior studies showed that polyhydroxylated styrylquinolines are potent HIV-1 integrase (IN) inhibitors that block the… (More)
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2000
2000
Modeling of the inhibition of retroviral integrases by styrylquinoline derivatives.
Styrylquinoline derivatives, known to be potent inhibitors of HIV-1 integrase, have been experimentally tested for their… (More)
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