stringent response

A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
CsrA protein regulates important cellular processes by binding to target mRNAs and altering their translation and/or stability… (More)
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Highly Cited
2008
Highly Cited
2008
The bacterial stringent response serves as a paradigm for understanding global regulatory processes. It can be triggered by… (More)
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Highly Cited
2008
Highly Cited
2008
The stringent response to amino acid starvation, whereby stable RNA synthesis is curtailed in favour of transcription of amino… (More)
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Highly Cited
2002
Highly Cited
2002
During conditions of nutrient deprivation, ribosomes are blocked by uncharged tRNA at the A site. The stringent factor RelA binds… (More)
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Highly Cited
2002
Highly Cited
2002
The stringent response in Bacillus subtilis was characterized by using proteome and transcriptome approaches. Comparison of… (More)
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Highly Cited
2002
Highly Cited
2002
When conditions cause bacterial growth to stop, extensive reprogramming of physiology and gene expression allows for the cell's… (More)
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Review
2001
Review
2001
Microbial adaptation to environmental stress plays an important role in survival. It is necessary to understand the mechanisms… (More)
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Highly Cited
2001
Highly Cited
2001
During nutrient starvation, Escherichia coli elicits a stringent response involving the ribosome-associated protein RelA… (More)
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Highly Cited
2000
Highly Cited
2000
The stringent response utilizes hyperphosphorylated guanine [(p)ppGpp] as a signaling molecule to control bacterial gene… (More)
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Highly Cited
1991
Highly Cited
1991
The stringent response was elicited in the antibiotic producer Streptomyces coelicolor A3(2) either by amino acid depletion… (More)
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