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stem cell fate determination

The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the… 
National Institutes of Health

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stem cell fate commitment

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Caspases and their substrates
Protease biology is intimately linked to the functional consequences of substrate cleavage events. Human caspases are a family of… 
Review
2015
Review
2015
Mechanism of regulation of stem cell differentiation by matrix stiffness
Stem cell behaviors are regulated by multiple microenvironmental cues. As an external signal, mechanical stiffness of the… 
Highly Cited
2013
Highly Cited
2013
miR‐21 modulates the ERK–MAPK signaling pathway by regulating SPRY2 expression during human mesenchymal stem cell differentiation
The ERK–MAPK signaling pathway plays a pivotal role during mesenchymal stem cell (MSC) differentiation. Studies have demonstrated… 
Highly Cited
2011
Highly Cited
2011
miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells.
miR-137 is a brain-enriched microRNA. Its role in neural development remains unknown. Here we show that miR-137 has an essential… 
Review
2010
Review
2010
Nanotopographical Control of Stem Cell Differentiation
Stem cells have the capacity to differentiate into various lineages, and the ability to reliably direct stem cell fate… 
Highly Cited
2010
Highly Cited
2010
Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination.
Embryonic stem (ES) cells are under precise control of both intrinsic self-renewal gene regulatory network and extrinsic growth… 
Highly Cited
2009
Highly Cited
2009
Notch Promotes Radioresistance of Glioma Stem Cells
Radiotherapy represents the most effective nonsurgical treatments for gliomas. However, gliomas are highly radioresistant and… 
Highly Cited
2009
Highly Cited
2009
Auxin-induced WUS expression is essential for embryonic stem cell renewal during somatic embryogenesis in Arabidopsis
Somatic embryogenesis requires auxin and establishment of the shoot apical meristem (SAM). WUSCHEL (WUS) is critical for stem… 
Review
2009
Review
2009
The natural and engineered 3D microenvironment as a regulatory cue during stem cell fate determination.
The concept of using stem cells as self-renewing sources of healthy cells in regenerative medicine has existed for decades, but… 
Review
2006
Review
2006
POZ for effect--POZ-ZF transcription factors in cancer and development.
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