stem cell fate determination
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Protease biology is intimately linked to the functional consequences of substrate cleavage events. Human caspases are a family of… Expand Stem cell behaviors are regulated by multiple microenvironmental cues. As an external signal, mechanical stiffness of the… Expand miR-137 is a brain-enriched microRNA. Its role in neural development remains unknown. Here we show that miR-137 has an essential… Expand Radiotherapy represents the most effective nonsurgical treatments for gliomas. However, gliomas are highly radioresistant and… Expand Stem cells have the capacity to differentiate into various lineages, and the ability to reliably direct stem cell fate… Expand Embryonic stem (ES) cells are under precise control of both intrinsic self-renewal gene regulatory network and extrinsic growth… Expand To study the role of cell-extracellular matrix (ECM) interactions, microscale approaches provide the potential to perform high… Expand The concept of using stem cells as self-renewing sources of healthy cells in regenerative medicine has existed for decades, but… Expand Somatic embryogenesis requires auxin and establishment of the shoot apical meristem (SAM). WUSCHEL (WUS) is critical for stem… Expand The BTB/POZ-ZF [Broad complex, Tramtrack, Bric à brac (BTB) or poxvirus and zinc finger (POZ)-zinc finger] protein family… Expand