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stampidine

Known as: stavudine-5'-(p-bromophenyl methoxyalaninyl phosphate) 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

DideoxynucleotidesStavudineThymidine Monophosphate
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Preclinical and first-in-human phase I clinical evaluation of stampidine, a potent anti-HIV pharmaceutical drug candidate.
The rationally designed novel anti-HIV drug candidate Stampidine exhibited (a) remarkable subnanomolar to low nanomolar in vitro… 
Review
2006
Review
2006
Unmet Challenges in HIV Therapy and Potential of Stampidine
  • F. Uckun
  • Arzneimittelforschung
  • 2006
  • Corpus ID: 29087706
Fig. 1: Global perspective of HIV crisis (2005) [2]. Since the first cases of Acquired Immune Deficiency Syndrome (AIDS) were… 
2005
2005
In vitro Anti-HIV Potency of Stampidine Alone and in Combination with Standard Anti-HIV Drugs
Summary The purpose of the present study was to compare the in vitro anti-HIV potency of stampidine (CAS 217178-62-6), a novel… 
2004
2004
In vitro Activity of Stampidine against Primary Clinical Human Immunodeficiency Virus Isolates
Summary The in vitro activity profile of stampidine (CAS 217178-62-6, STAMP) was examined against clinical isolates of HIV-1. In… 
2003
2003
In Vivo Antiretroviral Activity of Stampidine in Chronically Feline Immunodeficiency Virus-Infected Cats
ABSTRACT Here we report the antiretroviral activity of the experimental nucleoside reverse transcriptase inhibitor (NRTI… 
2003
2003
Toxicity and Pharmacokinetics of Stampidine in Mice and Rats
Summary The in vivo toxicity and pharmacokinetics of stampidine (CAS 217178-62-6), an aryl phosphate derivative of stavudine (CAS… 
2003
2003
Development and Evaluation of a Thermoreversible Ovule Formulation of Stampidine, a Novel Nonspermicidal Broad-Spectrum Anti-Human Immunodeficiency Virus Microbicide1
Abstract Stampidine [2′,3′-didehydro-2′,3′-dideoxythymidine 5′-[p-bromophenyl methoxyalaninyl phosphate], a prodrug of stavudine… 
2002
2002
Stampidine Is a Potent Inhibitor of Zidovudine- and Nucleoside Analog Reverse Transcriptase Inhibitor-Resistant Primary Clinical Human Immunodeficiency Virus Type 1 Isolates with Thymidine Analog…
ABSTRACT We report the antiretroviral activity of stavudine-5′-(p-bromophenyl methoxyalaninyl phosphate) (stampidine [STAMP]), a… 
2002
2002
Metabolism of stavudine-5'-[p-bromophenyl methoxyalaninyl phosphate], stampidine, in mice, dogs, and cats.
We examined the pharmacokinetics and metabolism of the experimental nucleoside reverse transcriptase inhibitor compound… 
1998
1998
D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] as a potent and non-toxic anti-human immunodeficiency virus agent.
Three aryl phosphate derivatives of 2',3'-didehydro-2',3'-dideoxythymidine (d4T) were tested for their anti-human… 
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