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spirolide C

National Institutes of Health

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Spiro Compounds

Papers overview

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2019
2019
Synthesis of 7,6-Spirocyclic Imine with Butenolide Ring Provides Evidence for the Relative Configuration of Marine Toxin 13-desMe Spirolide C.
Efficient synthesis of the partial structure of marine toxin 13-desMe spirolide C was achieved via the selective Diels-Alder… 
2015
2015
Approches synthétiques aux fragments spiroimines du 13-desméthyle spirolide C et de la gymnodimine
La Gymnodimine et le 13-desmethyle Spirolide C sont des neurotoxines macrocycliques a imine cyclique. Elles ont ete isolees dans… 
2012
2012
Studies toward the synthesis of spirolide C: exploration into the formation of the 23-membered all-carbon macrocyclic framework.
The synthesis of two complex subunits en route to spirolide C is described. A key alkyllithium addition to an aldehyde joins the… 
2012
2012
Catalytic Asymmetric Bond Constructions in Complex Molecule Synthesis. An Approach to the Synthesis of Spirolide C and the Development of Enantioselective Enolate Hydroxylation Reactions
The asymmetric synthesis of spirolide C, a highly potent marine toxin, has been investigated in our laboratory. The construction… 
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