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Diarrhetic shellfish toxins
Diarrhetic Shellfish Poisoning
DSP is caused by certain toxins produced by marine organisms, in large concentration, that can contaminate certain seafood and result in poisoning when humans eat such seafood.
Isolation and structure of yessotoxin, a novel polyether compound implicated in diarrhetic shellfish poisoning
Structures and Configurations of Ciguatoxin from the Moray Eel Gymnothorax javanicus and Its Likely Precursor from the Dinoflagellate Gambierdiscus toxicus
Ciguatoxin (CTX) is the toxic principle of ciguatera, which is responsible for the most widespread food poisoning of nonbacterial origin. The toxin, isolated from the moray eel Gymnothorax javanicus,…
Stereochemical Determination of Acyclic Structures Based on Carbon-Proton Spin-Coupling Constants. A Method of Configuration Analysis for Natural Products.
- N. Matsumori, D. Kaneno, M. Murata, Hideshi Nakamura, K. Tachibana
- ChemistryThe Journal of organic chemistry
- 20 January 1999
This J-based configuration analysis was applied to the stereochemical elucidation of carboxylic acid 5 derived from zooxanthellatoxin and proven to be a practical method even for natural products with complicated structures.
A three-dimensional movie of structural changes in bacteriorhodopsin
Time-resolved serial femtosecond crystallography at an x-ray free electron laser shows how motions are choreographed as bR transports protons uphill against a transmembrane concentration gradient.
Isolation and structural elucidation of the causative toxin of the diarrhetic shellfish poisoning.
Comparison of the toxin by various spectrometries with okadaic acid isolated from the marine dinoflagellate Prorocentrum lima established that dinophysistoxin-1 is 35S-methyl okADAic acid C45H70O13, confirming that this organism is the progenitor of the toxins.
Grease matrix as a versatile carrier of proteins for serial crystallography
A grease-matrix carrier for protein microcrystals is introduced and the structures of lysozyme, glucose isomerase, thaumatin and fatty acid–binding protein type 3 are obtained under ambient conditions at a resolution of or finer than 2 Å.
TOXINS PRODUCED BY BENTHIC DINOFLAGELLATES
Nine species of benthic dinoflagellates collected in subtropical waters were cultured, extracted, and tested for mouse lethality, ichthyotoxicity, and hemolytic activity. Hemolytic activity was…
Okadaic Acid as the Causative Toxin of Diarrhetic Shellfish Poisoning in Europe
The toxic principle in mussels collected in France, Sweden, the Netherlands, and Spain that caused diarrhetic shellfish poisoning was identified to be okadaic acid by its chromatographic properties…