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spiradoline

National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

AnalgesicsAnti-Arrhythmia AgentsDiureticsPyrrolidines

Narrower (1)

U 62066

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Fischer rats are more sensitive than Lewis rats to the suppressive effects of morphine and the aversive kappa-opioid agonist spiradoline.
Data have suggested that rats avoid intake of an otherwise palatable saccharin cue when paired with a drug of abuse, at least, in… 
Highly Cited
2009
Highly Cited
2009
The Effects of Repeated Opioid Administration on Locomotor Activity: II. Unidirectional Cross-Sensitization to Cocaine
Sensitization refers to an increase in sensitivity to the effects of a drug and is believed to play a role in the etiology of… 
2007
2007
Nociceptin/orphanin FQ blocks the antinociception induced by mu, kappa and delta opioid agonists on the cold water tail-flick test.
2005
2005
Characterization of a Novel Bivalent Morphinan Possessing κ Agonist and μ Agonist/Antagonist Properties
Previous research has shown that compounds with mixed κ and μ activity may have utility for the treatment of cocaine abuse and… 
1999
1999
Ligands for opioid and sigma-receptors improve cardiac electrical stability in rat models of post-infarction cardiosclerosis and stress.
1996
1996
Prolonged antagonism of morphine-induced locomotor stimulation by κ opioid agonists: Enhancement by prior morphine exposure
1996
1996
Kappa opioid receptor agonists inhibit sigma-1 (σ1) receptor binding in guinea-pig brain, liver and spleen: autoradiographical evidence
1993
1993
Effects of spiradoline mesylate, a selective kappa-opioid-receptor agonist, on the central dopamine system with relation to mouse locomotor activity and analgesia.
Neurochemical and behavioral investigations were made to assess the role of central dopaminergic systems in mouse locomotor… 
1990
1990
Modulation of Histamine Release in the Rat Brain by K‐Opioid Receptors
Abstract: The opioid modulation of histamine release was studied in rat brain slices labeled with L‐[3H]histidine. The K+‐induced… 
1988
1988
Cardiovascular depressant effects of the kappa opioid receptor agonists U50488H and spiradoline mesylate.
The cardiovascular effects of the selective kappa opioid receptor agonists U50488H and spiradoline mesylate were examined in… 
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