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spiradoline

 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Our previous work indicated that pretreatment with the selective kappa-opioid receptor (KOPr) agonist, U69593, attenuated the… Expand
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Highly Cited
2007
Highly Cited
2007
κ Opioid agonists were at one time proposed as candidate pharmacotherapies for cocaine addiction, mainly because of their ability… Expand
2003
2003
The present study examined the influence of sex on the antinociceptive effects of (−)-pentazocine, morphine and spiradoline in… Expand
2000
2000
Previous research has shown that rats consuming a sucrose solution and chow are more sensitive to the analgesic actions of… Expand
Highly Cited
1998
Highly Cited
1998
We are developing a system to control G protein signaling in vivo to regulate a broad range of physiologic responses. Our system… Expand
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Highly Cited
1997
Highly Cited
1997
Opioid drugs act on specific receptors which are principally classified into μ, δ and κ subtypes. Spiradoline (U‐62066E) is a… Expand
Highly Cited
1995
Highly Cited
1995
Two kappa agonists, U50,488 and spiradoline, produced dose-related acute decreases in both morphine and cocaine self… Expand
Highly Cited
1993
Highly Cited
1993
The effects of the indirect dopamine receptor agonist cocaine in the striatum on levels of mRNAs of the immediate-early gene c… Expand
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1993
1993
To evaluate the role of opioids in Tourette's syndrome (TS), we performed a dose-response study of the behavioral and… Expand
Highly Cited
1988
Highly Cited
1988
Spiradoline (a congener of the kappa opioid agonist, U-50488H) was evaluated for analgesic and related activities in rodents. In… Expand