spiradoline

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2016
051019882016

Papers overview

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2009
2009
Our previous work indicated that pretreatment with the selective kappa-opioid receptor (KOPr) agonist, U69593, attenuated the… (More)
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2000
2000
The results of a previous study in rats indicated that spiradoline has pharmacologically selective discriminative effects that… (More)
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Highly Cited
1998
Highly Cited
1998
We are developing a system to control G protein signaling in vivo to regulate a broad range of physiologic responses. Our system… (More)
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1997
1997
1. Opioid drugs act on specific receptors which are principally classified into mu, delta and kappa subtypes. Spiradoline (U… (More)
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Highly Cited
1995
Highly Cited
1995
Two kappa agonists, U50,488 and spiradoline, produced dose-related acute decreases in both morphine and cocaine self… (More)
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1994
1994
This study compared the potency of mixed-action opioids (i.e., agonist-antagonists) and pure antagonists to block the… (More)
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1993
1993
To evaluate the role of opioids in Tourette's syndrome (TS), we performed a dose-response study of the behavioral and… (More)
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1991
1991
This study represents the initial step in assessing the discriminative effects of spiradoline (U62,066), a potent congener of the… (More)
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1991
1991
1. The mechanism of the diuretic effect of the kappa opioid receptor agonist spiradoline was investigated in 10 healthy male… (More)
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1988
1988
Spiradoline (a congener of the kappa opioid agonist, U-50488H) was evaluated for analgesic and related activities in rodents. In… (More)
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