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spiradoline

National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

AnalgesicsAnti-Arrhythmia AgentsDiureticsPyrrolidines

Narrower (1)

U 62066

Papers overview

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Highly Cited
2009
Highly Cited
2009
The Effects of Repeated Opioid Administration on Locomotor Activity: II. Unidirectional Cross-Sensitization to Cocaine
Sensitization refers to an increase in sensitivity to the effects of a drug and is believed to play a role in the etiology of… 
2008
2008
Effects of environmental enrichment on sensitivity to mu, kappa, and mixed-action opioids in female rats
2007
2007
Nociceptin/orphanin FQ blocks the antinociception induced by mu, kappa and delta opioid agonists on the cold water tail-flick test.
2005
2005
Characterization of a Novel Bivalent Morphinan Possessing κ Agonist and μ Agonist/Antagonist Properties
Previous research has shown that compounds with mixed κ and μ activity may have utility for the treatment of cocaine abuse and… 
2005
2005
Discriminative stimulus effects of spiradoline, a kappa-opioid agonist
This study represents the initial step in assessing the discriminative effects of spiradoline (U62,066), a potent congener of the… 
1999
1999
Ligands for opioid and sigma-receptors improve cardiac electrical stability in rat models of post-infarction cardiosclerosis and stress.
1996
1996
Prolonged antagonism of morphine-induced locomotor stimulation by κ opioid agonists: Enhancement by prior morphine exposure
1996
1996
Kappa opioid receptor agonists inhibit sigma-1 (σ1) receptor binding in guinea-pig brain, liver and spleen: autoradiographical evidence
1993
1993
Effects of spiradoline mesylate, a selective kappa-opioid-receptor agonist, on the central dopamine system with relation to mouse locomotor activity and analgesia.
Neurochemical and behavioral investigations were made to assess the role of central dopaminergic systems in mouse locomotor… 
1988
1988
Cardiovascular depressant effects of the kappa opioid receptor agonists U50488H and spiradoline mesylate.
The cardiovascular effects of the selective kappa opioid receptor agonists U50488H and spiradoline mesylate were examined in… 
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