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spiradoline

National Institutes of Health

Papers overview

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2005
2005
Previous research has shown that compounds with mixed κ and μ activity may have utility for the treatment of cocaine abuse and… 
Review
2003
Review
2003
The selective kappa-opioid receptor agonist spiradoline mesylate (U62,066E), an arylacetamide, was synthesized with the intention… 
Highly Cited
1998
Highly Cited
1998
We are developing a system to control G protein signaling in vivo to regulate a broad range of physiologic responses. Our system… 
Highly Cited
1997
Highly Cited
1997
Opioid drugs act on specific receptors which are principally classified into μ, δ and κ subtypes. Spiradoline (U‐62066E) is a… 
Highly Cited
1993
Highly Cited
1993
The effects of the indirect dopamine receptor agonist cocaine in the striatum on levels of mRNAs of the immediate-early gene c… 
Highly Cited
1988
Highly Cited
1988
Spiradoline (a congener of the kappa opioid agonist, U-50488H) was evaluated for analgesic and related activities in rodents. In…