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spindle elongation

The cell cycle process in which the distance is lengthened between poles of the spindle. [GOC:ai]
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

mitotic spindle elongation

Broader (2)

nuclear chromosome segregationspindle organization

Papers overview

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Highly Cited
2009
Highly Cited
2009
Kif15 Cooperates with Eg5 to Promote Bipolar Spindle Assembly
BACKGROUND The formation of a bipolar spindle is an essential step during cell division. Bipolar spindle assembly is driven by… Expand
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Highly Cited
2009
Highly Cited
2009
Phospho-regulated interaction between kinesin-6 Klp9p and microtubule bundler Ase1p promotes spindle elongation.
The spindle midzone-composed of antiparallel microtubules, microtubule-associated proteins (MAPs), and motors-is the structure… Expand
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Highly Cited
2008
Highly Cited
2008
APC/CCdh1 Targets Aurora Kinase to Control Reorganization of the Mitotic Spindle at Anaphase
BACKGROUND Control of mitotic cell cycles by the anaphase-promoting complex or cyclosome (APC/C) ubiquitin ligase depends on its… Expand
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Highly Cited
2007
Highly Cited
2007
Polo-Like Kinase Controls Vertebrate Spindle Elongation and Cytokinesis
During cell division, chromosome segregation must be coordinated with cell cleavage so that cytokinesis occurs after chromosomes… Expand
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Highly Cited
2006
Highly Cited
2006
The NoCut Pathway Links Completion of Cytokinesis to Spindle Midzone Function to Prevent Chromosome Breakage
During anaphase, spindle elongation pulls sister chromatids apart until each pair is fully separated. In turn, cytokinesis… Expand
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Highly Cited
2005
Highly Cited
2005
The protein kinase Kin4 inhibits exit from mitosis in response to spindle position defects.
Accurate nuclear position is essential for each daughter cell to receive one DNA complement. In budding yeast, a surveillance… Expand
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Highly Cited
1998
Highly Cited
1998
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis.
We have identified a novel human protein, PRC1, that is involved in cytokinesis. PRC1 is a good substrate for several CDKs in… Expand
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Highly Cited
1998
Highly Cited
1998
Dynamics of centromeres during metaphase-anaphase transition in fission yeast: Dis1 is implicated in force balance in metaphase bipolar spindle.
In higher eukaryotic cells, the spindle forms along with chromosome condensation in mitotic prophase. In metaphase, chromosomes… Expand
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Highly Cited
1993
Highly Cited
1993
Disruption of mitotic spindle orientation in a yeast dynein mutant.
Dynein motor isoforms have been implicated as potential kinetochore-associated motors that power chromosome-to-pole movements… Expand
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Highly Cited
1987
Highly Cited
1987
Interzone microtubule behavior in late anaphase and telophase spindles
We have studied microtubule behavior in late anaphase and telophase spindles of PtK1 cells, using fluoresceinated tubulin (DTAF… Expand
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