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spindle elongation

The cell cycle process in which the distance is lengthened between poles of the spindle. [GOC:ai]
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

mitotic spindle elongation

Broader (2)

nuclear chromosome segregationspindle organization

Papers overview

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Highly Cited
2009
Highly Cited
2009
Kif15 Cooperates with Eg5 to Promote Bipolar Spindle Assembly
BACKGROUND The formation of a bipolar spindle is an essential step during cell division. Bipolar spindle assembly is driven by… Expand
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Highly Cited
2009
Highly Cited
2009
Phospho-regulated interaction between kinesin-6 Klp9p and microtubule bundler Ase1p promotes spindle elongation.
The spindle midzone-composed of antiparallel microtubules, microtubule-associated proteins (MAPs), and motors-is the structure… Expand
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Highly Cited
2006
Highly Cited
2006
The NoCut Pathway Links Completion of Cytokinesis to Spindle Midzone Function to Prevent Chromosome Breakage
During anaphase, spindle elongation pulls sister chromatids apart until each pair is fully separated. In turn, cytokinesis… Expand
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Highly Cited
2005
Highly Cited
2005
The protein kinase Kin4 inhibits exit from mitosis in response to spindle position defects.
Accurate nuclear position is essential for each daughter cell to receive one DNA complement. In budding yeast, a surveillance… Expand
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Highly Cited
2004
Highly Cited
2004
Laser Microsurgery in Fission Yeast Role of the Mitotic Spindle Midzone in Anaphase B
INTRODUCTION During anaphase B in mitosis, polymerization and sliding of overlapping spindle microtubules (MTs) contribute to the… Expand
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Highly Cited
1998
Highly Cited
1998
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis.
We have identified a novel human protein, PRC1, that is involved in cytokinesis. PRC1 is a good substrate for several CDKs in… Expand
Highly Cited
1998
Highly Cited
1998
Dynamics of centromeres during metaphase-anaphase transition in fission yeast: Dis1 is implicated in force balance in metaphase bipolar spindle.
In higher eukaryotic cells, the spindle forms along with chromosome condensation in mitotic prophase. In metaphase, chromosomes… Expand
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Highly Cited
1997
Highly Cited
1997
Mitotic spindle function in Saccharomyces cerevisiae requires a balance between different types of kinesin-related motors.
Two Saccharomyces cerevisiae kinesin-related motors, Cin8p and Kip1p, perform an essential role in the separation of spindle… Expand
Highly Cited
1993
Highly Cited
1993
Disruption of mitotic spindle orientation in a yeast dynein mutant.
Dynein motor isoforms have been implicated as potential kinetochore-associated motors that power chromosome-to-pole movements… Expand
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Highly Cited
1992
Highly Cited
1992
CENP-E is a putative kinetochore motor that accumulates just before mitosis
THE mechanics of chromosome movement, mitotic spindle assembly and spindle elongation have long been central questions of cell… Expand
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