FAQ

spindle elongation

The cell cycle process in which the distance is lengthened between poles of the spindle. [GOC:ai]

Topic mentions per year

Topic mentions per year

1966-2017
05101519662017

Related topics

Related topics

3 relations

Narrower (1)

mitotic spindle elongation
regulation of spindle elongation

Broader (1)

spindle organization

Related mentions per year

Related mentions per year

1966-2018
1960198020002020
spindle elongation
spindle organization
mitotic spindle elongation
regulation of spindle elongation

Papers overview

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2009
2009
Phosphorylation-dependent protein interactions at the spindle midzone mediate cell cycle regulation of spindle elongation.
The metaphase-to-anaphase transition is one of the most dramatic and highly regulated steps in cell division. At anaphase onset… (More)
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Highly Cited
2007
Highly Cited
2007
Polo-Like Kinase Controls Vertebrate Spindle Elongation and Cytokinesis
During cell division, chromosome segregation must be coordinated with cell cleavage so that cytokinesis occurs after chromosomes… (More)
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Highly Cited
2007
Highly Cited
2007
Kinesin-5 acts as a brake in anaphase spindle elongation
Bipolar kinesin-5 motors, essential in diverse organisms, can generate positive sliding forces between overlapped interpolar… (More)
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Highly Cited
2006
Highly Cited
2006
The NoCut Pathway Links Completion of Cytokinesis to Spindle Midzone Function to Prevent Chromosome Breakage
During anaphase, spindle elongation pulls sister chromatids apart until each pair is fully separated. In turn, cytokinesis… (More)
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Highly Cited
2002
Highly Cited
2002
Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle
EB1 is an evolutionarily conserved protein that localizes to the plus ends of growing microtubules. In yeast, the EB1 homologue… (More)
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Highly Cited
2001
Highly Cited
2001
Stu2 Promotes Mitotic Spindle Elongation in Anaphase
During anaphase, mitotic spindles elongate up to five times their metaphase length. This process, known as anaphase B, is… (More)
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Highly Cited
1998
Highly Cited
1998
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis.
We have identified a novel human protein, PRC1, that is involved in cytokinesis. PRC1 is a good substrate for several CDKs in… (More)
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Highly Cited
1995
Highly Cited
1995
Spindle dynamics and cell cycle regulation of dynein in the budding yeast, Saccharomyces cerevisiae
We have used time-lapse digital- and video-enhanced differential interference contrast (DE-DIC, VE-DIC) microscopy to study the… (More)
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Highly Cited
1993
Highly Cited
1993
Disruption of mitotic spindle orientation in a yeast dynein mutant.
Dynein motor isoforms have been implicated as potential kinetochore-associated motors that power chromosome-to-pole movements… (More)
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Highly Cited
1992
Highly Cited
1992
A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles.
Mitosis comprises a complex set of overlapping motile events, many of which involve microtubule-dependent motor enzymes. Here we… (More)
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