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sphingosine N-acyltransferase activity

Known as: dihydroceramide synthase activity, ceramide synthase activity, sphingosine acyltransferase activity 
Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine. [EC:2.3.1.24, MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN, PMID:12069845]
National Institutes of Health

Related topics

Related topics

2 relations
dihydroceramide desaturasedihydroceramide synthase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Assaying Ceramide Synthase Activity In Vitro and in Living Cells Using Liquid Chromatography-Mass Spectrometry.
Sphingolipids are one the major lipid families in eukaryotes, incorporating a diverse array of structural and signaling lipids… 
2016
2016
Abbreviations: alkyne-doxSA: (2S,3R)-2-aminooctadec-17-yn-3-ol; alkyne-SA: (2S,3R)-2- aminooctadec-17-yn-1,3-diol; ASTM-BODIPY: azido-sulfo-tetramethyl-BODIPY; CE: cholesterolester; Cer: ceramide…
1 Institute for Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland; 2 Center for Integrative Human Physiology… 
2014
2014
A Three-Step Assay for Ceramide Synthase Activity Using a Fluorescent Substrate and HPLC
Ceramides are a family of signalling lipids with diverse physiological functions that include pro-differentiative and pro… 
2012
2012
Myristic Acid Increases Dihydroceramide Δ4-Desaturase 1 (DES1) Activity in Cultured Rat Hepatocytes
Dihydroceramide Δ4-desaturase 1 (DES1) catalyzes the last step of the de novo ceramide biosynthesis, which consists of the… 
2000
2000
Measurement of ceramide synthase activity.
1997
1997
Induces k B-dependent Gene Expression in HL-60 Promyelocytic and Jurkat T Lymphoma Cells
The anthracycline antibiotic, daunorubicin, can induce programmed cell death (apoptosis) in cells. Recent work suggests that this… 
1995
1995
Fatty acyl-Co A: sphingosine acyltransferase in bovine brain mitochondria: its solubilization and reconstitution onto the membrane lipid liposomes.
Fatty acyl-Co A: sphingosine acyltransferase (ceramide synthase, EC 2.3.1.24) is mainly localized in the microsomal and… 
1968
1968
Phosphonolipids. XV. Synthesis of a dihydroceramide aminoethylphosphonate.
The first chemical synthesis of a dihydroceramide aminoethylphosphonate is described. It is a saturated representative of a new… 
1967
1967
Phosphonolipids. 13. Synthesis of dihydroceramide aminoethylphosphonates.
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