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sphingomyelin metabolic process

Known as: sphingomyelin metabolism 
The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the… Expand
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
OBJECTIVE Metabolic profiling of small molecules offers a snapshot of physiological processes. To identify metabolic signatures… Expand
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Review
2010
Review
2010
Sphingolipids in the membranes of neurons play important roles in signal transduction, either by modulating the localization and… Expand
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2010
2010
BACKGROUND Acid sphingomyelinase (ASM; EC 3.1.4.12) hydrolyses membrane sphingomyelin into the bioactive lipid ceramide and is… Expand
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Highly Cited
2005
Highly Cited
2005
Amyloid beta peptide (Aβ) has a key role in the pathological process of Alzheimer's disease (AD), but the physiological function… Expand
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2002
2002
A major physiological feedback mechanism of cholesterol in transcription of a number of lipid metabolism-related genes is… Expand
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2002
2002
Sphingomyelin is an important lipid component of cell membranes and lipoproteins that can be hydrolyzed by sphingomyelinases into… Expand
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Highly Cited
1992
Highly Cited
1992
We recently demonstrated that sphingosine enhances interleukin-1 beta (IL-1)-mediated prostaglandin E2 (PGE2) production in human… Expand
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Review
1990
Review
1990
Sphingomyelin is found in plasma membranes and related organelles (such as endocytic vesicles and lysosomes) of all tissues, as… Expand
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1983
1983
The metabolism of endogenous sphingomyelin labeled with 32P or [methyl-3H]choline and of exogenous [choline-methyl-3H], [32P… Expand
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1983
1983
The metabolism of [stearoyl-1-14C]- and [choline-methyl-14C]sphingomyelin, [stearoyl-1-14C]ceramide-1-phospho-N,N… Expand
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