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spermine synthase activity

Known as: S-adenosylmethioninamine:spermidine 3-aminopropyltransferase activity, spermidine aminopropyltransferase activity, spermine synthetase activity 
Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine. [EC:2.5.1.22]
National Institutes of Health

Papers overview

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2012
2012
Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis
Numerous studies have demonstrated a link between elevated polyamine biosynthesis and neoplastic growth, but the specific… 
Highly Cited
2000
Highly Cited
2000
Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea.
Mutant Gy male mice, which have previously been described as having disruption of the phosphate-regulating Phex gene and a… 
1984
1984
Reversal of the growth inhibitory effect of α-difluoromethylornithine by putrescine but not by other divalent cations
SummaryTreatment with α-difluoromethylornithine (DFMO), an enzyme-activated irreversible inhibitor of ornithine decarboxylase… 
Highly Cited
1976
Highly Cited
1976
Adenosylmethionine decarboxylase from various organisms: relation of the putrescine activation of the enzyme to the ability of the organism to synthesize spermine.
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