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sordarin

 
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Translation elongation factors facilitate protein synthesis by the ribosome. Previous studies identified two universally… Expand
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Highly Cited
2004
Highly Cited
2004
An 11.7-A-resolution cryo-EM map of the yeast 80S.eEF2 complex in the presence of the antibiotic sordarin was interpreted in… Expand
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Review
2003
Review
2003
Translation elongation factors are the workhorses of protein synthesis on the ribosome. They assist in elongating the nascent… Expand
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2001
2001
The sordarin class of natural products selectively inhibits fungal protein synthesis by impairing the function of eukaryotic… Expand
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1999
1999
Sordarin derivatives are selective inhibitors of fungal protein synthesis, which specifically impair elongation factor 2 (EF-2… Expand
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1999
1999
The natural product sordarin, a tetracyclic diterpene glycoside, selectively inhibits fungal protein synthesis by impairing the… Expand
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1998
1998
GM 193663, GM 211676, GM 222712, and GM 237354 are new semisynthetic derivatives of the sordarin class. The in vitro antifungal… Expand
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1998
1998
The target for sordarins in Candida albicans has been elucidated. Kinetic experiments of sordarin inhibition as well as… Expand
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1998
1998
GR135402, a sordarin derivative, was isolated in an antifungal screening program. GR135402, sordarin, and derivatives of both… Expand
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1998
1998
Sordarin derivatives are remarkably selective inhibitors of fungal protein synthesis. Available evidence points to a binding site… Expand
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