soluplus
National Institutes of Health
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The purpose of this study was to develop and evaluate a new formulation of ziprasidone (ZIP) for improved fasted state absorption…
The aim of this study was to improve the physicochemical properties of cocoa extract (CE) using hot-melt extrusion (HME) for…
Abstract The present study details the development of a small-scale spray-drying approach for the routine screening of amorphous…
Poor aqueous solubility is the main problem in development of effective formulation which affects stability and bioavailability…
: Telmisartan, a widely prescribed antihypertensive drug belongs to class II under BCS and exhibit low and variable oral…
CONTEXT
Drug dispersed in a polymer can improve bioavailability; dispersed amorphous drug undergoes recrystallization. Solid…
Soluplus, a graft copolymer of polyethylene glycol, vinyl caprolactam and vinyl acetate, is designed to solubilize poorly soluble…
Overview Purpose: Provide on the one hand an efficient screening tool for Hot-Melt Extrusion (HME) formulation development and…
The aim of the present study was to prepare solid dispersion (SD) of Lansoprazole (LSP) to improve its saturation solubility and…
Camptothecin (CPT), a potent antitumor drug, exhibits poor aqueous solubility and rapid conversion from the pharmacologically…