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solanezumab

Known as: Immunoglobulin G1, anti-(human beta-amyloid peptide) (humanized monoclonal LY2062430 heavy chain, disulfide with humanized monoclonal LY2062430 light chain, dimer) 
A humanized monoclonal antibody (IgG1) raised against amyloid beta peptides with Alzheimer disease treatment application. Solanezumab recognizes and… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Antibodies, Monoclonal, Humanized

Narrower (1)

LY 2062430
antigen binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Does Solanezumab Slow Cognitive Decline in Alzheimer Disease
Evidence suggests that the accumulation of amyloid-beta (Aβ) peptides in the brain is an important factor in the pathophysiology… 
2017
2017
From Nose to Brain: The Promise of Peptide Therapy for AlzheimerâÂÂsDisease and Other Neurodegenerative Diseases
The pathological hallmarks of Alzheimer’s disease (AD) are the deposition of extracellular senile plaques resulting from amyloid… 
2016
2016
UK scientists excited by surprise £2-billion government windfall
Cash to include fund modelled on DARPA, the US defence department’s research arm — but how much will go to basic research is… 
2016
2016
[Immunotherapy for Alzheimer's disease targeting Aβ].
Active and passive immunization of Alzheimer model mice with Aβ showed clearance of aggregated amyloid β deposits and improved… 
2015
2015
Margaret McCartney: The “breakthrough” drug that’s not been shown to help in Alzheimer’s disease
Our airwaves have been saturated, and the column inches heaved with the news: there’s been a breakthrough. “Landmark drug to… 
2014
2014
Phase 3 trials of solanezumab and bapineuzumab for Alzheimer's disease.
2014
2014
Doug Williams
Doug Williams, head of Research and Development at Biogen Idec, discusses remyelinating agents, Alzheimer's disease drugs and… 
2013
2013
Why “Subjective Cognitive Decline” Is Important
We have the target protein for Alzheimer, the antibody to knock out the protein, and the imaging test locating the protein in the… 
2011
2011
シンポジウム32―3 神経疾患に対する抗体療法 アルツハイマー病に対する抗体療法
In order to avoid Abeta-induced autoimmune encephalitis, several monoclonal and polyclonal antibodies are in clinical trials… 
1980
1980
News in brief
The UK Health Protection Agency (HPA) has warned about the need to develop new antibiotics before our current treatment options…