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sofalcone

Known as: 2-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Anti-Ulcer AgentChalcones

Narrower (2)

SU 88Solon

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Sofalcone Upregulates the Nuclear Factor (Erythroid-Derived 2)–Like 2/Heme Oxygenase-1 Pathway, Reduces Soluble fms–Like Tyrosine Kinase-1, and Quenches Endothelial Dysfunction: Potential Therapeutic…
Preeclampsia is a severe complication of pregnancy, characterized by hypertension, oxidative stress, and severe endothelial… 
2005
2005
Sofalcone, a mucoprotective agent, increases the cure rate of Helicobacter pylori infection when combined with rabeprazole, amoxicillin and clarithromycin.
AIM The mucoprotective agents, sofalcone and polaprezinc have anti-Helicobacter pylori (H pylori) activities. We determined the… 
Review
2001
Review
2001
Improvement in Atrophic Gastritis and Intestinal Metaplasia in Patients in Whom Helicobacter pylori Was Eradicated
Few long-term studies of chronic gastritis associated with Helicobacter pylori have been published. Kuipers (1) and Valle (2) and… 
Review
1998
Review
1998
The possible role of vascular endothelial growth factor (VEGF) in gastric ulcer healing: effect of sofalcone on VEGF release in vitro.
Angiogenesis plays an important role in gastric ulcer repair. Several growth factors are involved in angiogenesis and, of these… 
Review
1997
Review
1997
What other regimens are under investigation to treat Helicobacter pylori infection?
1996
1996
Effect of 10% ethanol and sofalcone on prostaglandin E2 content, mucus gel thickness, and experimental ulcers in the stomach of developing rats.
We studied the effects of a mild irritant, 10% ethanol, and sofalcone on the gastric mucosal defense mechanisms in newborn rats… 
1993
1993
Effect of sofalcone on gastric mucosal injury induced by ischemia-reperfusion and its antioxidant properties.
The effect of sofalcone on gastric mucosal injury induced by ischemia-reperfusion (I-R) injury was studied in rats. I-R injury… 
1990
1990
The Susceptibility of Campylobacter pylori to Antiulcer Agents and Antibiotics
The antibacterial activities of antiulcer agents and antibiotics against Campylobacter pylori were studied. The MC90 values of… 
Highly Cited
1989
Highly Cited
1989
Lipolytic activity of Campylobacter pylori: effect of sofalcone.
The lipolytic activity of Campylobacter pylori capable of gastric mucosal lipid degradation was investigated. The colonies of… 
1988
1988
Protection of gastric surface epithelial cells of rats by 16,16-dimethyl prostaglandin E2 and sofalcone, a synthetic flavonoid derivative of sophoradin, against ethanol.
We studied the effects of 16,16-dimethyl prostaglandin E2 (dm-PGE2) and sofalcone, a new antiulcer agent developed in Japan, on… 
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