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sofalcone

Known as: 2-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Anti-Ulcer AgentChalcones

Narrower (2)

SU 88Solon

Papers overview

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2013
2013
In vivo pharmacokinetic study on sofalcone in rats
Objective To study in vivo pharmacokinetic characteristics of sofalcone in rats.Methods HPLC method was established to determine… 
2005
2005
Sofalcone, a mucoprotective agent, increases the cure rate of Helicobacter pyloriinfection when combined with rabeprazole, amoxicillin and clarithromycin
AIM: The mucoprotective agents, sofalcone and polaprezinc have anti-Helicobacter pylori ( H pylori)activities. We determined the… 
1997
1997
In vitro dissolution test corresponding to in vivo dissolution of sofalcone formulations
Une cinetique de premier ordre et le modele de dissolution de Wagner ont ete mis en oeuvre afin d'obtenir un indice correct de… 
1987
1987
Enzymatic sulfation of gastric mucous glycoprotein in rat--changes in glycoprotein sulfotransferase activity with stress and anti-ulcer agent, sofalcone.
Enzymatic sulfation of mucous glycoprotein (GP) was studied in gastric mucosa of rat. After rat stomach was incubated with [35S… 
1986
1986
Effect of sofalcone on gastric mucosal prostaglandin metabolism in taurocholate induced gastritis in rats.
The effects of sodium taurocholate (TCA) and sofalcone on prostaglandin (PG) metabolism in rat gastric mucosa were examined. TCA… 
1986
1986
Effect of sofalcone on acute gastric mucosal lesions induced by aspirin and ethanol in reference to the biosynthesis of gastric mucosal glycoprotein.
Sofalcone prevented the formation of lesions by 50% ethanol and aspirin dose dependently, prevented the decrease in the gastric… 
1985
1985
Cytoprotective effect of sofalcone in the rat gastric mucosa.
The effect of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)-chalcone (sofalcone, Solon) on 0.6N HCl-induced gastric lesions… 
1985
1985
Anti-ulcer effect of isoprenyl flavonoids. III. Synthesis and anti-ulcer activity of metabolites of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone.
Five dihydrochalcone derivatives, 2'-carboxymethoxy-4, 4'-bis (3-methyl-2-butenyloxy) dihydrochalcone (M-6-b), 2', 4-bis… 
1985
1985
Effect of water immersion stress on the biosynthesis of rat gastric glycoproteins with or without sulfate.
The biosynthesis of rat gastric glycoproteins with or without sulfate was investigated in rats subjected to restraint and water… 
1984
1984
The studies on the role of gastric glycoproteins with reference to cytoprotection: protective effect of prostaglandin E2 and sofalcone on ethanol-induced necrosis.
The gastric cytoprotective action of prostaglandin E2 (PGE2) and sofalcone was studied in rats. The in vitro incorporating… 
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