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sofalcone

Known as: 2-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Anti-Ulcer AgentChalcones

Narrower (2)

SU 88Solon

Papers overview

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2015
2015
Sofalcone Upregulates the Nuclear Factor (Erythroid-Derived 2)–Like 2/Heme Oxygenase-1 Pathway, Reduces Soluble fms–Like Tyrosine Kinase-1, and Quenches Endothelial Dysfunction: Potential Therapeutic…
Preeclampsia is a severe complication of pregnancy, characterized by hypertension, oxidative stress, and severe endothelial… 
2002
2002
Analysis of Helicobacter pylori and nonsteroidal anti‐inflammatory drug‐induced gastric epithelial injury
Helicobacter pylori and nonsteroidal anti‐inflammatory drugs (NSAIDs) are important factors in gastric mucosal injury. However… 
1996
1996
Effect of 10% ethanol and sofalcone on prostaglandin E2 content, mucus gel thickness, and experimental ulcers in the stomach of developing rats.
We studied the effects of a mild irritant, 10% ethanol, and sofalcone on the gastric mucosal defense mechanisms in newborn rats… 
1993
1993
Effect of sofalcone on gastric mucosal injury induced by ischemia-reperfusion and its antioxidant properties.
The effect of sofalcone on gastric mucosal injury induced by ischemia-reperfusion (I-R) injury was studied in rats. I-R injury… 
1992
1992
Effect of Sofalcone on Localization of 15‐Hydroxyprostaglandin Dehydrogenase, An Enzyme That Metabolizes Prostaglandin E2, in Rat Gastric Mucosa: An Immunohistochemical Study
We identified the cells containing 15-hydroxyprostaglandin dehydrogenase (15-HPGD) in rat gastric mucosa and examined the effects… 
1991
1991
Enhancement of the physicochemical qualities of gastric mucus by sofalcone.
The effect of prolonged administration of an antiulcer drug, sofalcone, on the physicochemical properties of gastric mucus was… 
1990
1990
The Susceptibility of Campylobacter pylori to Antiulcer Agents and Antibiotics
The antibacterial activities of antiulcer agents and antibiotics against Campylobacter pylori were studied. The MC90 values of… 
1988
1988
Protection of gastric surface epithelial cells of rats by 16,16-dimethyl prostaglandin E2 and sofalcone, a synthetic flavonoid derivative of sophoradin, against ethanol.
We studied the effects of 16,16-dimethyl prostaglandin E2 (dm-PGE2) and sofalcone, a new antiulcer agent developed in Japan, on… 
1987
1987
Enzymatic sulfation of mucin in gastric mucosa: effect of sofalcone, sucralfate and aspirin.
A sulfotransferase activity which catalyzes the transfer of a sulfate group from 3'-phosphoadenosine-5'-phosphosulfate to gastric… 
1985
1985
Cytoprotective effect of sofalcone in the rat gastric mucosa.
The effect of 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)-chalcone (sofalcone, Solon) on 0.6N HCl-induced gastric lesions… 
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