smooth muscle cell apoptotic process

Known as: SMC apoptosis, programmed cell death, smooth muscle cells, smooth muscle cell programmed cell death by apoptosis 
Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive… (More)
National Institutes of Health

Papers overview

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2010
2010
p19(ARF) deficiency reduces macrophage and vascular smooth muscle cell apoptosis and aggravates atherosclerosis.
OBJECTIVES The goal of this study was to investigate the role in atherosclerosis of the tumor suppressor protein ARF (human p14… (More)
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Highly Cited
2010
Highly Cited
2010
Vascular smooth muscle cell apoptosis induces interleukin-1-directed inflammation: effects of hyperlipidemia-mediated inhibition of phagocytosis.
RATIONALE Atherosclerosis is characterized by lipid accumulation in the vessel wall, inflammation, and both macrophage and… (More)
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Highly Cited
2008
Highly Cited
2008
Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis.
BACKGROUND Vascular calcification is associated with increased morbidity and mortality in stage V chronic kidney disease, yet its… (More)
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Highly Cited
2007
Highly Cited
2007
Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway.
Previous studies have shown that mitofusin 2 (Mfn-2) (or hyperplasia suppressor gene [HSG]) inhibits vascular smooth muscle cell… (More)
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Review
2006
Review
2006
The emerging role of vascular smooth muscle cell apoptosis in atherosclerosis and plaque stability.
Accelerated atherosclerosis is both a cause and a consequence of chronic renal failure. Vascular smooth muscle cells (VSMCs) are… (More)
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Highly Cited
2005
Highly Cited
2005
Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension.
BACKGROUND We previously reported that administration of elastase inhibitors reverses fatal pulmonary arterial hypertension (PAH… (More)
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Highly Cited
2004
Highly Cited
2004
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis.
The pulmonary arteries (PA) in pulmonary arterial hypertension (PAH) are constricted and remodeled;. They have suppressed… (More)
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Highly Cited
2003
Highly Cited
2003
Tumor necrosis factor-alpha promotes macrophage-induced vascular smooth muscle cell apoptosis by direct and autocrine mechanisms.
OBJECTIVE We have previously shown that human macrophages induce human plaque vascular smooth muscle cell (VSMC) apoptosis by… (More)
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Highly Cited
1999
Highly Cited
1999
Determinants of vascular smooth muscle cell apoptosis after balloon angioplasty injury. Influence of redox state and cell phenotype.
We have observed that acute medial cell loss is an initial event in the response to vascular injury induced by balloon-catheter… (More)
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1999
1999
Regulation of vascular smooth muscle cell apoptosis. Modulation of bad by a phosphatidylinositol 3-kinase-dependent pathway.
Our objective was to define the signaling mechanisms by which mitogens such as insulin-like growth factor-I (IGF-I) regulate… (More)
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