slit diaphragm

A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
The nephron is the basic structural and functional unit of the vertebrate kidney. It is composed of a glomerulus, the site of… (More)
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Highly Cited
2005
Highly Cited
2005
Progressive kidney failure is a genetically and clinically heterogeneous group of disorders. Podocyte foot processes and the… (More)
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Highly Cited
2004
Highly Cited
2004
Nephrin is a key functional component of the slit diaphragm, the structurally unresolved molecular filter in renal glomerular… (More)
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Highly Cited
2003
Highly Cited
2003
Neph1-deficient mice develop nephrotic syndrome at birth, indicating the importance of this protein in the development of a… (More)
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Highly Cited
2002
Highly Cited
2002
We recently cloned a novel gene, NPHS2, involved in autosomal recessive steroid-resistant nephrotic syndrome. This gene encodes a… (More)
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Highly Cited
2001
Highly Cited
2001
NPHS2 was recently identified as a gene whose mutations cause autosomal recessive steroid-resistant nephrotic syndrome. Its… (More)
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Highly Cited
2001
Highly Cited
2001
CD2AP, an adapter protein containing multiple SH3 domains, plays a critical role in kidney function. Mice lacking CD2AP die soon… (More)
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Highly Cited
2000
Highly Cited
2000
The glomerular slit diaphragm between podocyte foot processes shares typical morphologic features with an adherens junction… (More)
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Highly Cited
1999
Highly Cited
1999
We describe here the size and location of nephrin, the first protein to be identified at the glomerular podocyte slit diaphragm… (More)
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Highly Cited
1974
Highly Cited
1974
The highly ordered, isoporous substructure of the glomerular slit diaphragm was revealed in rat and mouse kidneys fixed by… (More)
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