Substructure of the glomerular slit diaphragm in freeze-fractured normal rat kidney

@article{Karnovsky1975SubstructureOT,
  title={Substructure of the glomerular slit diaphragm in freeze-fractured normal rat kidney},
  author={M Karnovsky and G. Ryan},
  journal={The Journal of Cell Biology},
  year={1975},
  volume={65},
  pages={233 - 236}
}
In the renal glomerulus, the narrow slits between adjacent epithelial podocytes are bridged by a diaphragm (2, 8, 11). In rat and mouse kidneys fixed by perfusion with tannic acid and glutaraldehyde (TAG), it has recently been discovered that this diaphragm has a highly ordered, isoporous substructure (9). It consists of a regular array of alternating cross… CONTINUE READING