sipuleucel-T Injection [Provenge]
National Institutes of Health
Papers overview
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Currently, there is only one FDA approved cancer vaccine, PROVENGE® (sipuleucel-T). PROVENGE® is a personalized therapy for…
Although cancer vaccines could not show the evidence of their therapeutic effects in phase III clinical trials, two dendritic…
Extensive research in the area of active-specific immunotherapy has led to the approval of the first therapeutic cancer vaccine…
Dendritic cells (DCs) are essential for the initiation of T cell responses and are therefore an attractive target for cancer…
Prostate cancer (PC) is a malignancy which develops within the male prostate resulting from dietary habits, environmental aspects…
Immune-based therapies have demonstrated benefit in multiple clinical trials, and as we gain better knowledge of the mechanisms…
INTRODUCTION
Of the cancer gene therapy approaches, gene silencing, suicide/apoptosis inducing gene therapy, immunogene therapy…
Therapeutic vaccination against cancer is an important approach which, when combined with other therapies, can improve long-term…
The FDA has approved 2 new treatments for castration-resistant (formerly called hormone-refractory) prostate cancer. Sipuleucel-T…