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sinularin

 
National Institutes of Health

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2 relations

Broader (2)

DiterpenesHeterocyclic Compounds, 3-Ring

Papers overview

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Review
2020
Review
2020
Biological activities of sinularin: A literature-based review.
Sinularin ((9E)-13-hydroxy-4,9,13-trimethyl-17-methylidene-5,15-dioxatricyclo[12.3.1.0(4,6)] octadec-9-en-16-one) is the soft… Expand
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2019
2019
Sinularin exerts anti-tumor effects against human renal cancer cells relies on the generation of ROS
Sinularin, a soft corals-derived natural product, exerts anti-tumorigenic activity in various types of human cancer cells… Expand
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2018
2018
Sinularin Selectively Kills Breast Cancer Cells Showing G2/M Arrest, Apoptosis, and Oxidative DNA Damage
The natural compound sinularin, isolated from marine soft corals, is antiproliferative against several cancers, but its possible… Expand
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2018
2018
Chemical Constituents of Cultured Soft Coral Sinularia flexibilis
Diterpenes of the cembrane type are some of the most frequently encountered metabolites in soft corals of the order Alcyonacean… Expand
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2018
2018
Correction: Huang, H.W.; et al. Sinularin Selectively Kills Breast Cancer Cells Showing G2/M Arrest, Apoptosis, and Oxidative DNA Damage. Molecules 2018, 23, 849
The authors wish to make the following correction to their paper [1].[...]. 
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2017
2017
Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells
BackgroundSinularin isolated from the cultured soft coral Sinularia flexibilis has been reported to exert potent cytotoxic… Expand
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2017
2017
Sinularin induces oxidative stress‐mediated G2/M arrest and apoptosis in oral cancer cells
Soft corals‐derived natural product, sinularin, was antiproliferative against some cancers but its effect and detailed mechanism… Expand
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2016
2016
Sinularin Induces Apoptosis through Mitochondria Dysfunction and Inactivation of the pI3K/Akt/mTOR Pathway in Gastric Carcinoma Cells
Sinularin is an active compound isolated from the cultured soft coral Sinularia flexibilis. In this study, we investigated the… Expand
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2012
2012
Sinularin from Indigenous Soft Coral Attenuates Nociceptive Responses and Spinal Neuroinflammation in Carrageenan-Induced Inflammatory Rat Model
Three decades ago, the marine-derived compound sinularin was shown to have anti-edematous effects on paw edema induced by… Expand
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2012
2012
Proteomic investigation of anti‐tumor activities exerted by sinularin against A2058 melanoma cells
The extracts from soft corals have been increasingly investigated for biomedical and therapeutic purposes. The aim of this study… Expand
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