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sialyl Lewis x

National Institutes of Health

Papers overview

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2007
2007
Glycomic mapping of pseudomucinous human ovarian cyst glycoproteins: Identification of Lewis and sialyl Lewis glycotopes
Expression of sialyl Lewis x (sLex) and sialyl Lewis a (sLea) on cell‐surface glycoproteins endows cells with the ability to… 
Highly Cited
2005
Highly Cited
2005
Sialyl Lewis antigens: association with MUC5AC protein and correlation with post-operative recurrence of non-small cell lung cancer.
Highly Cited
2004
Highly Cited
2004
Molecular basis of the dynamic strength of the sialyl Lewis X--selectin interaction.
The selectins are Ca(2+)-dependent cell adhesion molecules that facilitate the initial attachment of leukocytes to the vascular… 
Highly Cited
2003
Highly Cited
2003
Structurally Distinct Requirements for Binding of P-selectin Glycoprotein Ligand-1 and Sialyl Lewis x to Anaplasma phagocytophilum and P-selectin*
Colonization of neutrophils by the bacterium Anaplasma phagocytophilum causes the disease human granulocytic ehrlichiosis. The… 
2000
2000
Synthesis of the C-glycoside analogue of a novel sialyl Lewis X mimetic.
Sialyl Lewis X (sLex) mimetics that can function as selectin antagonists have received considerable attention in connection with… 
1998
1998
Ligand Recognition by E- and P-Selectin: Chemoenzymatic Synthesis and Inhibitory Activity of Bivalent Sialyl Lewis x Derivatives and Sialyl Lewis x Carboxylic Acids
Described is the preparation of five sLex dimers and five sLex carboxylic acids by coupling chemoenzymatically synthesized amino… 
1997
1997
Distinct substrate specificities of five human alpha-1,3-fucosyltransferases for in vivo synthesis of the sialyl Lewis x and Lewis x epitopes.
Five different human alpha-1,3-fucosyltransferase genes, the Fuc-TIII, Fuc-TIV, Fuc-TV, Fuc-TVI and Fuc-TVII genes, have been… 
1995
1995
Increased expression of sialyl Lewis A and sialyl Lewis X in liver metastases of human colorectal carcinoma.
Sialyl Lewis A (SLA) and sialyl Lewis X (SLX) have been shown to be specific ligands for endothelial leukocyte adhesion molecule… 
1995
1995
Sialyl Lewis X moiety on rat polymorphonuclear leukocytes responsible for binding to rat E-selectin.
We investigated the presence of the carbohydrate ligand for E-selectin on the cell surface of rat polymorphonuclear leukocytes… 
Highly Cited
1994
Highly Cited
1994
The P-selectin glycoprotein ligand from human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamine.
We previously demonstrated that P-selectin binds with high affinity to a trace, homodimeric glycoprotein ligand on human myeloid… 
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