sespendole
National Institutes of Health
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Sespendole is an indole sesquiterpene alkaloid bearing two isoprenyl groups, one of which is highly oxidized. Herein, we disclose…
Indole sesquiterpene sespendole, which has been isolated from the filamentous fungus Pseudobotrytis terrestris FKA‐25, is a…
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Two possible diastereomers of the indole moiety of sespendole were synthesized from 3-hydroxy-4-nitrobenzaldehyde in a highly…
Sespendole was isolated as an inhibitor of lipid droplet formation in macrophages from the culture broth of a fungal strain…
A new fungal metabolite named sespendole was isolated as an inhibitor of lipid droplet synthesis in mouse macrophages from the…
Sespendole is the first reported fungal metabolite having an indolosesquiterpene core structure. The biosynthesis of sespendole…