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sergeolide

Known as: 3,13-Ethano-1H,10H-furo(3,4-c)furo(2',3':6,7)naphtho(2,3-b)pyran-3(3aH)-carboxylic acid, 4-(acetyloxy)-4,5,6a,7,7a,8,12a,13-octahydro-14,15-dihydroxy-8,12a-dimethyl-5,10-dioxo-, methyl ester, (3S-(3alpha,3aalpha,4alpha,6aalpha,7abeta,8beta,12a)), Sergiolide 
A quassinoid phytochemical isolated from Cedronia granatensis and other plant species with potential antineoplastic activity. (NCI04)
National Institutes of Health

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Quassins

Papers overview

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1992
1992
Cytotoxic quassinoids from Cedronia granatensis.
The NCI in vitro primary disease-oriented antitumor screen has been used to select and guide the fractionation of the organic and… 
1985
1985
In vitro and in vivo assessement of the antimalarial activity of sergeolide.
The antimalarial activity of sergeolide (a quassinoid from PICROLEMMA PSEUDOCOFFEA) was investigated both, IN VITRO on PLASMODIUM… 
1985
1985
In vitro and in vivo assessement of the antimalarial activity of sergeolide.
The antimalarial activity of sergeolide (a quassinoid from PICROLEMMA PSEUDOCOFFEA) was investigated both, IN VITRO on PLASMODIUM… 
1984
1984
15-Deacetylsergeolide, a potent antileukemic quassinoid from Picrolemma pseudocoffea.
Investigation of the leaf extract of Picrolemma pseudocoffea afforded a new antineoplastic quassinoid, 15-deacetylsergeolide (3… 
1982
1982
ISOLATION AND STRUCTURE OF SERGEOLIDE , A POTENT CYTOTOXIC QUASSINOID
The quassinoids2, the bitter constituents of the Simaroubaceae, have been shown to possess diverse and potentially useful… 
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