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Activity of quassinoids as antifeedants against aphids
TLDR
Only quassin showed no phytotoxic effects and is therefore the most promising compound for further development in antifeedant activity against the aphidMyzus persicae.
Roquefortine and isofumigaclavine A, metabolites fromPenicillium roqueforti
The structures of two metabolites fromPenicillium roqueforti, designated roquefortine and isofumigaclavine A, have been determined by chemical and spectroscopic studies.
Immunotherapy of an ascitic rat hepatoma with cord factor (trehalose‐6, 6′‐dimycolate) and synthetic analogues
TLDR
The ability of cord factor and a range of shorter carbon chain fatty acid trehalose diesters to suppress growth of an ascitic rat hepatoma has been examined and compared with that of whole, living BCG organisms.
The natural occurrence of melianodiol and its diacetate in Samadera madagascariensis(simaroubaceae): model experiments on melianodiol directed towards simarolide
“From Samadera madagascariensis melianodiol and its diacetate have been isolated; biogenetic experiments directed towards simarolide have been carried on melianodiol.”
Structural analysis of purified platelet-activating factor by lipases
TLDR
Results of these experiments suggest that PAF is a 1-lyso-glycerophospholipid, a newly described mediator of anaphylaxis which has been implicated in the deposition of immune complexes in acute serum sickness in rabbits.
[Semi-synthesis and proposed structure of platelet-activating factor (P.A.F.): PAF-acether an alkyl ether analog of lysophosphatidylcholine].
TLDR
It is proposed that the molecular structure of platelet-activating factor, a mediator of inflammation obtained from blood leukocytes, macrophages, and platelets themselves, is 1-0-alkyl-2-acetyl-glyceryl-3-phosphorylcholine, which is currently unknown among the numerous substances capable of inducing platelet aggregation and release.
Quassinoid Bitter Principles.
  • J. Polonsky
  • Chemistry
    Fortschritte der Chemie organischer Naturstoffe…
  • 1973
TLDR
The Simaroubaceae form a large botanical family of mostly pantropical distribution; only a few representatives (such as Ailanthus) extend into temperate regions and many new bitter constituents have been isolated and had their structures elucidated.
Evaluation of limonoids against the murine P388 lymphocytic leukemia cell line.
TLDR
A structure/activity study of selected limonoids from two plant families against the murine P-388 lymphocytic leukemia system found the presence of both a 19 leads to 28 lactol and a 14,15 beta-epoxide group was found especially important for pronounced inhibition of the PS in vitro cell line.
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