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seraspenide

National Institutes of Health

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goralatide

Papers overview

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1997
1997
In vitro study of Seraspenide on HIV‐induced inhibition of granulopoiesis
Soluble(s) factor(s) produced by HIV‐infected cells have been implicated in bone marrow dysfunction observed in AIDS patients. We… 
1996
1996
The synthetic tetrapeptide AcSDKP protects cells that reconstitute long-term bone marrow stromal cultures from the effects of mafosfamide (Asta Z 7654).
The tetrapeptide AcSDKP (Seraspenide) has been described as an inhibitor of CFU-S entry into DNA synthesis; as a result, its… 
Review
1995
Review
1995
Inhibitory peptides in hematopoiesis.
This paper will review the present knowledge on two small chemically unrelated peptides, the pentapeptide pGlu-Glu-Asp-Cys-Lys… 
1995
1995
AcSDKP serum concentrations vary during chemotherapy in patients with acute myeloid leukaemia
AcSDKP is a physiological negative regulator of cell proliferation in mammals. In Ara‐C‐treated mice its plasmatic concentrations… 
1994
1994
[Inhibitors of hematopoiesis: from physiology to therapy].
A balance of both stimulatory and inhibitory factors interfere with gross and precise hematopoiesis regulation. A number of… 
1994
1994
Seraspenide (AcSDKP) mediated protection of hematopoietic stem cells in a hyperthermic purging protocol.
Review
1993
Review
1993
Ways of minimising hematopoietic damage induced by radiation and cytostatic drugs--the possible role of inhibitors.
1993
1993
The tetrapeptide acserasplyspro (seraspenide), a hematopoietic inhibitor, may reduce the in vitro toxicity of 3′‐Azido‐3′‐deoxythymidine to human hematopoietic progenitors
3′‐azido‐3′‐deoxythymidine (AZT), the main antiviral drug used in AIDS treatment, is known to induce anemia and neutropenia… 
1992
1992
Séraspénide (acétylSDKP) : étude en phase I-II d'un inhibiteur de l'hématopoïèse la protégeant de la toxicité de monochimiothérapies aracytine et ifosfamide
Le Seraspenide est un tetrapeptide present chez l'homme (acetyl-Ser-Asp-Lys-Pro). initialement isole de la moelle de foetus de… 
1992
1992
[Seraspenide (acetylSDKP): phase I-II trial study of inhibitor of hematopoiesis protects against toxicity of aracytine and ifosfamide monochemotherapies].
Seraspenide, a synthetic tetrapeptide, inhibits cell cycle entry of normal hematopoietic stem cells. In mice it protects… 
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