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sepiapterin reductase activity

Known as: 7,8-dihydrobiopterin:NADP+ oxidoreductase activity 
Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+. [EC:1.1.1.153]
National Institutes of Health

Papers overview

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Review
2006
Review
2006
Mutations in the BH4‐metabolizing genes GTP cyclohydrolase I, 6‐pyruvoyl‐tetrahydropterin synthase, sepiapterin reductase, carbinolamine‐4a‐dehydratase, and dihydropteridine reductase
Tetrahydrobiopterin (BH4) deficiencies are a highly heterogeneous group of disorders with several hundred patients, and so far a… 
1996
1996
Characterization of sepiapterin reductase activity from Drosophila melanogaster.
Highly Cited
1990
Highly Cited
1990
Control of tetrahydrobiopterin synthesis in T lymphocytes by synergistic action of interferon-gamma and interleukin-2.
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