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selurampanel
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
ABSTRACT Introduction: Epilepsy is one of the most serious neurological conditions, affecting almost 50 million people around the… Expand
Review
2018
Review
2018
ABSTRACT Introduction: Epilepsy is a neurological disorder that significantly impacts the quality of life of affected persons… Expand
2017
2017
&NA; Poor water solubility of drugs fuels complex formulations and jeopardizes patient access to medication. Simplifying these… Expand
2017
2017
Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist
A series of potent quinazolinedione sulfonamide antagonists of the α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole‐propionic acid (AMPA… Expand
Review
2017
Review
2017
Topiramate is a new antiepileptic drug (AED) that has been approved worldwide (in more than 80 countries) for the treatment of… Expand
Review
2016
Review
2016
Currently information is available for 20 potential anti-seizure drugs in clinical development. They include candidates with… Expand
2015
2015
Examine the efficacy of a competitive α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA)/kainate glutamate receptor… Expand
Review
2014
Review
2014
Introduction: AMPA-type glutamate receptor (AMPAR) antagonism is under development as a novel mechanism of action for… Expand