selurampanel

A series of potent quinazolinedione sulfonamide antagonists of the α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA… (More)

Poor water solubility of drugs fuels complex formulations and jeopardizes patient access to medication. Simplifying these… (More)

Currently information is available for 20 potential anti-seizure drugs in clinical development. They include candidates with… (More)

OBJECTIVE Examine the efficacy of a competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate glutamate… (More)

INTRODUCTION AMPA-type glutamate receptor (AMPAR) antagonism is under development as a novel mechanism of action for… (More)