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secnidazole

Known as: 1-(2'-hydroxypropyl)-2-methyl-5- nitroimidazole 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Antiprotozoal AgentsMetronidazole
Itraconazole / secnidazoleanalogs & derivatives

Narrower (2)

SabimaSecnidal

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Molecularly imprinted solid phase extraction of fluconazole from pharmaceutical formulations.
2012
2012
Design, synthesis and antimicrobial activities of nitroimidazole derivatives containing 1,3,4-oxadiazole scaffold as FabH inhibitors.
Highly Cited
2008
Highly Cited
2008
Formulation and Evaluation of PLA and PLGA In Situ Implants Containing Secnidazole and/or Doxycycline for Treatment of Periodontitis
The purpose of this study is to formulate in situ implants containing doxycycline hydrochloride and/or secnidazole that could be… 
Highly Cited
2007
Highly Cited
2007
Simultaneous determination of seven nitroimidazole residues in meat by using HPLC-UV detection with solid-phase extraction.
Highly Cited
2003
Highly Cited
2003
Dientamoeba fragilis, a neglected cause of diarrhea, successfully treated with secnidazole.
OBJECTIVE To evaluate the pathogenicity of Dientamoeba fragilis by comparing it with Giardia lamblia and to investigate the… 
Review
1999
Review
1999
Pharmacokinetics and Pharmacodynamics of the Nitroimidazole Antimicrobials
Metronidazole, the prototype nitroimidazole antimicrobial, was originally introduced to treat Trichomonas vaginalis, but is now… 
Review
1996
Review
1996
Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis.
Secnidazole is structurally related to the commonly used 5-nitroimidazoles metronidazole and tinidazole. These drugs share a… 
Highly Cited
1992
Highly Cited
1992
Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture
The expression of several forms of cytochrome P450 including P450 1A2, 2D6, 2E1, and 3A was investigated in human hepatocytes… 
1984
1984
Electron-capture gas chromatographic assays of 5-nitroimidazole class of antimicrobials in blood.
Highly Cited
1983
Highly Cited
1983
Generation of free radicals from metronidazole and other nitroimidazoles by Tritrichomonas foetus.
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