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secnidazole

Known as: 1-(2'-hydroxypropyl)-2-methyl-5- nitroimidazole 
 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Antiprotozoal AgentsMetronidazole
Itraconazole / secnidazoleanalogs & derivatives

Narrower (2)

SabimaSecnidal

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Susceptibility of bacterial vaginosis (BV)-associated bacteria to secnidazole compared to metronidazole, tinidazole and clindamycin.
Secnidazole, a 5-nitroimidazole with a longer half-life, is structurally related to metronidazole and tinidazole. For treatment… Expand
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Highly Cited
2008
Highly Cited
2008
Formulation and Evaluation of PLA and PLGA In Situ Implants Containing Secnidazole and/or Doxycycline for Treatment of Periodontitis
The purpose of this study is to formulate in situ implants containing doxycycline hydrochloride and/or secnidazole that could be… Expand
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2004
2004
ICH guidance in practice: establishment of inherent stability of secnidazole and development of a validated stability-indicating high-performance liquid chromatographic assay method.
The degradation behaviour of secnidazole was investigated under different stress degradation (hydrolytic, oxidative, photolytic… Expand
2004
2004
Spectrophotometric determination of metronidazole and secnidazole in pharmaceutical preparations.
A rapid and sensitive spectrophotometric method is proposed for determination of metronidazole and secnidazole. The method… Expand
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Highly Cited
2003
Highly Cited
2003
Dientamoeba fragilis, a neglected cause of diarrhea, successfully treated with secnidazole.
OBJECTIVE To evaluate the pathogenicity of Dientamoeba fragilis by comparing it with Giardia lamblia and to investigate the… Expand
Review
2003
Review
2003
Nitroheterocyclic drugs with broad spectrum activity
Abstract.The group of biologically active nitroheterocyclic compounds includes various 5- and 2-nitroimidazoles and 5-nitrofurans… Expand
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2003
2003
A randomized trial comparing mebendazole and secnidazole for the treatment of giardiasis
Abstract To compare the efficacy of the two drugs in the treatment of giardiasis, 146 children (aged 5–15 years) with confirmed… Expand
Review
1999
Review
1999
Pharmacokinetics and Pharmacodynamics of the Nitroimidazole Antimicrobials
Metronidazole, the prototype nitroimidazole antimicrobial, was originally introduced to treat Trichomonas vaginalis, but is now… Expand
1998
1998
Lansoprazole and secnidazole with clarithromycin, amoxycillin or pefloxacin in the eradication of Helicobacter pylori in a developing country
A number of triple drug regimens using proton pump inhibitors and two antibiotics have been evaluated in the West and reported to… Expand
Highly Cited
1992
Highly Cited
1992
Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture
The expression of several forms of cytochrome P450 including P450 1A2, 2D6, 2E1, and 3A was investigated in human hepatocytes… Expand
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